5orx A 1.88 BS01 ADP A 1 G140 G142 V147 K162 A213 T217 E260 L263 D274 G14 G16 V21 K36 A87 T91 E134 L137 D148 D256 K258 E260 N261 D274 T292 D130 K132 E134 N135 D148 T166 2.7.11.1 0004672,0005524,0006468 O14965 29045126 401 QWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLAGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPS 5orx A 1.88 BS02 MG A 1 N261 D274 N135 D148 D256 K258 E260 N261 D274 T292 D130 K132 E134 N135 D148 T166 2.7.11.1 0004672,0005524,0006468 O14965 29045126 402 QWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLAGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPS 5orx A 1.88 BS03 A6H A 1 E175 L178 Y199 H201 E49 L52 Y73 H75 D256 K258 E260 N261 D274 T292 D130 K132 E134 N135 D148 T166 2.7.11.1 0004672,0005524,0006468 ic50=308uM -logKd/Ki=3.51, IC50=308uM O14965 29045126 404 QWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLAGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPS