5okt A 2.13 BS01 9XK A 1 I15 L25 A36 L85 G86 L135 I12 L22 A33 L82 G83 L132 2.7.11.1,2.7.11.26 0004672,0005524,0006468 ic50=317nM -logKd/Ki=6.03, IC50=0.93uM P48730 29630366 301 RVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLK 5okt B 2.13 BS01 9XK B 1 I15 L25 E34 A36 L84 L85 G86 L135 I12 L22 E31 A33 L81 L82 G83 L132 2.7.11.1,2.7.11.26 0004672,0005524,0006468 ic50=317nM P48730 29630366 301 RVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRHIPYRENTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLK 5okt C 2.13 BS01 9XK C 1 I15 A36 L84 L85 G86 L135 I12 A32 L75 L76 G77 L126 2.7.11.1,2.7.11.26 0004672,0005524,0006468 ic50=317nM P48730 29630366 301 RVGNRYRLGRKIGGSFGDIYLGTDIAAGEEVAIKLECPQLHIESKIYKMMQGGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLK 5okt D 2.13 BS01 9XK D 1 A36 M82 E83 L84 L85 G86 L135 L138 A28 M70 E71 L72 L73 G74 L123 L126 2.7.11.1,2.7.11.26 0004672,0005524,0006468 ic50=317nM P48730 29630366 301 LRVGNRYRLGRKGDIYLGTDIAAGEEVAIKLECHPQLHIESKIYKMMQGGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLK