5ogl A 2.7 BS01 peptide B 0 T54 D56 N146 R147 Y152 E315 T316 I317 M318 E319 N321 R331 L374 W463 W464 D465 G482 V575 T53 D55 N145 R146 Y151 E314 T315 I316 M317 E318 N320 R330 L373 W462 W463 D464 G481 V574 2.4.99.19 0000287,0004576,0005886,0006486,0016020,0016757,0018279,0046872 B9KDD4 29058712 10 ~ 17 ELQQNFTDNNSIKYTAILILIAFAFSVLARLYWVAWASEFYEFFFNDQLMITTNDGYAFAEGARDMIAGFHQPNDLSYFGSSLSTLTYWLYSILPFSFESIILYMSTFFASLIVVPIILIAREYKLTTYGFIAALLGSIANSYYNRTMSGYYDTDMLVLVLPMLILLTFIRLTINKDIFTLLLSPVFIMIYLWWYPSSYSLNFAMIGLFGLYTLVFHRKEKIFYLTIALMIIALSMLAWQYKLALIVLLFAIFAFKEEKINFYMIWALIFISILILHLSGGLDPVLYQLKFYVFKASDVQNLKDAAFMYFNVNETIMEVNTIDPEVFMQRISSSVLVFILSFIGFILLLKDHKSMLLALPMLALGFMALRAGLRFTIYAVPVMALGFGYFLYAFFNFLEKKQIKLSLRNKNILLILIAFFSISPALMHIYYYKSSTVFTSYEASILNDLKNKAQREDYVVAWWDYGYPIRYYSDVKTLIDGGKHLGKDNFFSSFVLSKEQIPAANMARLSVEYTEKSFKENYPDVLKAMVKDYQKTSAKDFLESLNDPNFKIDTPKTRDVYIYMPYRMLRIMPVVAQFANTNPDNGEQEKSLFFSQANPLDQDGSITLDNGVEISNDYRSLKIEGNSIPLKAFVDIESITNGKFYYNEIDSKAQIYLLYLREYKSYVILDESLYNSSYIQMFLLNQYDQDLFEQITNDTRAKIYRLK 5ogl A 2.7 BS02 MN A 1 D56 D154 D55 D153 2.4.99.19 0000287,0004576,0005886,0006486,0016020,0016757,0018279,0046872 B9KDD4 29058712 801 ELQQNFTDNNSIKYTAILILIAFAFSVLARLYWVAWASEFYEFFFNDQLMITTNDGYAFAEGARDMIAGFHQPNDLSYFGSSLSTLTYWLYSILPFSFESIILYMSTFFASLIVVPIILIAREYKLTTYGFIAALLGSIANSYYNRTMSGYYDTDMLVLVLPMLILLTFIRLTINKDIFTLLLSPVFIMIYLWWYPSSYSLNFAMIGLFGLYTLVFHRKEKIFYLTIALMIIALSMLAWQYKLALIVLLFAIFAFKEEKINFYMIWALIFISILILHLSGGLDPVLYQLKFYVFKASDVQNLKDAAFMYFNVNETIMEVNTIDPEVFMQRISSSVLVFILSFIGFILLLKDHKSMLLALPMLALGFMALRAGLRFTIYAVPVMALGFGYFLYAFFNFLEKKQIKLSLRNKNILLILIAFFSISPALMHIYYYKSSTVFTSYEASILNDLKNKAQREDYVVAWWDYGYPIRYYSDVKTLIDGGKHLGKDNFFSSFVLSKEQIPAANMARLSVEYTEKSFKENYPDVLKAMVKDYQKTSAKDFLESLNDPNFKIDTPKTRDVYIYMPYRMLRIMPVVAQFANTNPDNGEQEKSLFFSQANPLDQDGSITLDNGVEISNDYRSLKIEGNSIPLKAFVDIESITNGKFYYNEIDSKAQIYLLYLREYKSYVILDESLYNSSYIQMFLLNQYDQDLFEQITNDTRAKIYRLK 5ogl A 2.7 BS03 MN A 2 Q73 D76 D475 Q72 D75 D474 2.4.99.19 0000287,0004576,0005886,0006486,0016020,0016757,0018279,0046872 B9KDD4 29058712 802 ELQQNFTDNNSIKYTAILILIAFAFSVLARLYWVAWASEFYEFFFNDQLMITTNDGYAFAEGARDMIAGFHQPNDLSYFGSSLSTLTYWLYSILPFSFESIILYMSTFFASLIVVPIILIAREYKLTTYGFIAALLGSIANSYYNRTMSGYYDTDMLVLVLPMLILLTFIRLTINKDIFTLLLSPVFIMIYLWWYPSSYSLNFAMIGLFGLYTLVFHRKEKIFYLTIALMIIALSMLAWQYKLALIVLLFAIFAFKEEKINFYMIWALIFISILILHLSGGLDPVLYQLKFYVFKASDVQNLKDAAFMYFNVNETIMEVNTIDPEVFMQRISSSVLVFILSFIGFILLLKDHKSMLLALPMLALGFMALRAGLRFTIYAVPVMALGFGYFLYAFFNFLEKKQIKLSLRNKNILLILIAFFSISPALMHIYYYKSSTVFTSYEASILNDLKNKAQREDYVVAWWDYGYPIRYYSDVKTLIDGGKHLGKDNFFSSFVLSKEQIPAANMARLSVEYTEKSFKENYPDVLKAMVKDYQKTSAKDFLESLNDPNFKIDTPKTRDVYIYMPYRMLRIMPVVAQFANTNPDNGEQEKSLFFSQANPLDQDGSITLDNGVEISNDYRSLKIEGNSIPLKAFVDIESITNGKFYYNEIDSKAQIYLLYLREYKSYVILDESLYNSSYIQMFLLNQYDQDLFEQITNDTRAKIYRLK 5ogl A 2.7 BS04 9UB A 1 D56 F60 Y79 Y196 S198 Q289 Y293 M368 R375 F376 Y379 Y468 D55 F59 Y78 Y195 S197 Q288 Y292 M367 R374 F375 Y378 Y467 2.4.99.19 0000287,0004576,0005886,0006486,0016020,0016757,0018279,0046872 -logKd/Ki=4.31, Kd=48.5uM B9KDD4 29058712 803 ELQQNFTDNNSIKYTAILILIAFAFSVLARLYWVAWASEFYEFFFNDQLMITTNDGYAFAEGARDMIAGFHQPNDLSYFGSSLSTLTYWLYSILPFSFESIILYMSTFFASLIVVPIILIAREYKLTTYGFIAALLGSIANSYYNRTMSGYYDTDMLVLVLPMLILLTFIRLTINKDIFTLLLSPVFIMIYLWWYPSSYSLNFAMIGLFGLYTLVFHRKEKIFYLTIALMIIALSMLAWQYKLALIVLLFAIFAFKEEKINFYMIWALIFISILILHLSGGLDPVLYQLKFYVFKASDVQNLKDAAFMYFNVNETIMEVNTIDPEVFMQRISSSVLVFILSFIGFILLLKDHKSMLLALPMLALGFMALRAGLRFTIYAVPVMALGFGYFLYAFFNFLEKKQIKLSLRNKNILLILIAFFSISPALMHIYYYKSSTVFTSYEASILNDLKNKAQREDYVVAWWDYGYPIRYYSDVKTLIDGGKHLGKDNFFSSFVLSKEQIPAANMARLSVEYTEKSFKENYPDVLKAMVKDYQKTSAKDFLESLNDPNFKIDTPKTRDVYIYMPYRMLRIMPVVAQFANTNPDNGEQEKSLFFSQANPLDQDGSITLDNGVEISNDYRSLKIEGNSIPLKAFVDIESITNGKFYYNEIDSKAQIYLLYLREYKSYVILDESLYNSSYIQMFLLNQYDQDLFEQITNDTRAKIYRLK