5nge A 2.35 BS01 8WK A 1 Y224 D295 Q297 Q351 L406 M407 R408 F409 H456 D459 N460 H461 Y465 Y514 Y13 D84 Q86 Q140 L195 M196 R197 F198 H245 D248 N249 H250 Y254 Y295 N218 C223 H464 D481 N7 C12 H253 D270 3.4.19.12 0004843,0016579 Kd=65nM -logKd/Ki=7.19, Kd=65nM Q93009 29045389 601 GYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRK 5nge B 2.35 BS01 8WK B 1 D295 V296 Q297 Q351 L406 M407 R408 F409 H456 D459 N460 H461 Y465 Y514 D86 V87 Q88 Q133 L169 M170 R171 F172 H219 D222 N223 H224 Y228 Y273 N218 C223 H464 D481 N9 C14 H227 D244 3.4.19.12 0004843,0016579 Kd=65nM Q93009 29045389 601 HTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYSDRREDYYDIQLSIKGKKNIFESFVDYVAVEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQK