5n5s A 2.3 BS01 NAP A 1 V167 S168 P169 W170 N171 L176 K194 A196 S197 R228 T246 G247 S248 I251 E267 L268 C302 E396 F398 Y463 V150 S151 P152 W153 N154 L159 K177 A179 S180 R211 T229 G230 S231 I234 E250 L251 C285 E379 F381 Y446 N171 K194 E267 C302 E396 E474 N154 K177 E250 C285 E379 E457 1.2.1.9 0000166,0008911,0016491,0016620 Kd=31uM A9SS48 28749584 600 TPKKYNIFLASKPVDGDRKWLDVTNKYTNDVAAKVPQATHKDIDDAIDAAVAAAPAMAAMGAYERKAVLEKVVAELKNRFEEIAQTLTMESGKPIKDARGEVTRTIDTFQVAAEESVRIYGEHIPLDISARNKGLQGIVKKFPIGPVSMVSPWNFPLNLVAHKVAPAIAVGCPFVLKPASRTPLSALILGEILHKIEELPLGAFSILPVSREDADMFTVDERFKLLTFTGSGPIGWDMKARAGKKKVVMELGGNAPCIVDDYVPDLDYTIQRLINGGFYQGGQSCIHMQRLYVHERLYDEVKEGFVAAVKKLKMGNPFEEDTYLGPMISESAAKGIEDWVKEAVAKGGKLLTGGNRKGAFIEPTVIEDVPIEANARKEEIFGPVVLLYKYSDFKEAVKECNNTHYGLQSGIFTKDLNKAFYAFEHMEVGGVILNDSPALRVDSQPYGGLKDSGIQREGVKYAMDDMLETKVLVMRNVGTL 5n5s B 2.3 BS01 NAP B 1 V167 S168 P169 W170 N171 L176 K194 A196 S197 R228 A231 T246 G247 S248 I251 E267 L268 C302 E396 F398 Y463 V151 S152 P153 W154 N155 L160 K178 A180 S181 R212 A215 T230 G231 S232 I235 E251 L252 C286 E380 F382 Y447 N171 K194 E267 C302 E396 E474 N155 K178 E251 C286 E380 E458 1.2.1.9 0000166,0008911,0016491,0016620 Kd=31uM A9SS48 28749584 502 VTPKKYNIFLASKPVDGDRKWLDVTNKYTNDVAAKVPQATHKDIDDAIDAAVAAAPAMAAMGAYERKAVLEKVVAELKNRFEEIAQTLTMESGKPIKDARGEVTRTIDTFQVAAEESVRIYGEHIPLDISARNKGLQGIVKKFPIGPVSMVSPWNFPLNLVAHKVAPAIAVGCPFVLKPASRTPLSALILGEILHKIEELPLGAFSILPVSREDADMFTVDERFKLLTFTGSGPIGWDMKARAGKKKVVMELGGNAPCIVDDYVPDLDYTIQRLINGGFYQGGQSCIHMQRLYVHERLYDEVKEGFVAAVKKLKMGNPFEEDTYLGPMISESAAKGIEDWVKEAVAKGGKLLTGGNRKGAFIEPTVIEDVPIEANARKEEIFGPVVLLYKYSDFKEAVKECNNTHYGLQSGIFTKDLNKAFYAFEHMEVGGVILNDSPALRVDSQPYGGLKDSGIQREGVKYAMDDMLETKVLVMRNVGTL 5n5s C 2.3 BS01 NAP C 1 V167 S168 P169 W170 N171 L176 K194 A196 S197 R228 T246 G247 S248 I251 E267 L268 C302 E396 F398 Y463 V151 S152 P153 W154 N155 L160 K178 A180 S181 R212 T230 G231 S232 I235 E251 L252 C286 E380 F382 Y447 N171 K194 E267 C302 E396 E474 N155 K178 E251 C286 E380 E458 1.2.1.9 0000166,0008911,0016491,0016620 Kd=31uM A9SS48 28749584 501 VTPKKYNIFLASKPVDGDRKWLDVTNKYTNDVAAKVPQATHKDIDDAIDAAVAAAPAMAAMGAYERKAVLEKVVAELKNRFEEIAQTLTMESGKPIKDARGEVTRTIDTFQVAAEESVRIYGEHIPLDISARNKGLQGIVKKFPIGPVSMVSPWNFPLNLVAHKVAPAIAVGCPFVLKPASRTPLSALILGEILHKIEELPLGAFSILPVSREDADMFTVDERFKLLTFTGSGPIGWDMKARAGKKKVVMELGGNAPCIVDDYVPDLDYTIQRLINGGFYQGGQSCIHMQRLYVHERLYDEVKEGFVAAVKKLKMGNPFEEDTYLGPMISESAAKGIEDWVKEAVAKGGKLLTGGNRKGAFIEPTVIEDVPIEANARKEEIFGPVVLLYKYSDFKEAVKECNNTHYGLQSGIFTKDLNKAFYAFEHMEVGGVILNDSPALRVDSQPYGGLKDSGIQREGVKYAMDDMLETKVLVMRNVGTL 5n5s D 2.3 BS01 NAP D 1 V167 S168 P169 W170 N171 L176 K194 S197 R228 A231 T246 G247 S248 I251 E267 L268 C302 E396 F398 Y463 V150 S151 P152 W153 N154 L159 K177 S180 R211 A214 T229 G230 S231 I234 E250 L251 C285 E379 F381 Y446 N171 K194 E267 C302 E396 E474 N154 K177 E250 C285 E379 E457 1.2.1.9 0000166,0008911,0016491,0016620 Kd=31uM A9SS48 28749584 503 TPKKYNIFLASKPVDGDRKWLDVTNKYTNDVAAKVPQATHKDIDDAIDAAVAAAPAMAAMGAYERKAVLEKVVAELKNRFEEIAQTLTMESGKPIKDARGEVTRTIDTFQVAAEESVRIYGEHIPLDISARNKGLQGIVKKFPIGPVSMVSPWNFPLNLVAHKVAPAIAVGCPFVLKPASRTPLSALILGEILHKIEELPLGAFSILPVSREDADMFTVDERFKLLTFTGSGPIGWDMKARAGKKKVVMELGGNAPCIVDDYVPDLDYTIQRLINGGFYQGGQSCIHMQRLYVHERLYDEVKEGFVAAVKKLKMGNPFEEDTYLGPMISESAAKGIEDWVKEAVAKGGKLLTGGNRKGAFIEPTVIEDVPIEANARKEEIFGPVVLLYKYSDFKEAVKECNNTHYGLQSGIFTKDLNKAFYAFEHMEVGGVILNDSPALRVDSQPYGGLKDSGIQREGVKYAMDDMLETKVLVMRNVGTL