5mm7 A 5.1 BS01 GTP A 1 G10 Q11 A12 D98 A100 N101 S140 G143 G144 T145 G146 I171 T179 E183 N206 Y224 N228 G9 Q10 A11 D87 A89 N90 S129 G132 G133 T134 G135 I160 T168 E172 N195 Y213 N217 3.6.5.- 0000226,0000278,0005200,0005525,0005737,0005856,0005874,0007017,0016787,0031514,0046872 P02550 31288039 501 RECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFSVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRGHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYEPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDS 5mm7 A 5.1 BS02 MG A 1 D98 T145 D87 T134 3.6.5.- 0000226,0000278,0005200,0005525,0005737,0005856,0005874,0007017,0016787,0031514,0046872 P02550 31288039 502 RECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFSVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRGHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYEPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDS 5mm7 B 5.1 BS01 TA1 B 1 V23 D26 D226 H229 L230 A233 S236 F272 P274 T276 P360 R369 V22 D25 D223 H226 L227 A230 S233 F269 P271 T273 P357 R358 ? 0000226,0000278,0003924,0005200,0005515,0005525,0005737,0005856,0005874,0007017,0046872 EC50=520nM P02554 31288039 501 REIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEAAGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQD 5mm7 B 5.1 BS02 GDP B 1 G10 Q11 C12 N101 S140 G143 G144 T145 G146 Y224 N228 G9 Q10 C11 N98 S137 G140 G141 T142 G143 Y221 N225 ? 0000226,0000278,0003924,0005200,0005515,0005525,0005737,0005856,0005874,0007017,0046872 P02554 31288039 502 REIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEAAGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQD 5mm7 K 5.1 BS01 MG K 1 G186 K187 T188 H189 G126 K127 T128 H129 ? 0003777,0005524,0007018,0008017 A0A0D1DQH0 31288039 500 NNSNELDRKRSDAGESNIQVVVRVRGQAPNEPKRTAPGILTTSGPRCQQIDVAIEAPQVSSSSAIASTSNLVQESATRQKSYHFDQVFGPEADQGMVYQDVVGPILEEVMSGYNCTIFAYGQTGTGKTHTMEGDLTSQMGTYSSEAGIIPRSLYRLFHTLELSKEDYSVKATFIELYNEELRDLLSIDSSTSSAEPSSSATATKEPQHALRMYDDARGKGVVIQGLEEVALKDAAHGLSVLRRGSQKRQIAATNCNEQSSRSHSVFTMTVFIKDKGSRGEDVLKIGKLNLVDLAGSENIGRSGAENKRAREAGMINQSLLTLGRVINALVEKNSHIPYRESKLTRLLQESLGGRTKTCIIATVSQERANIEETLSTLDYALRAKSIKNRPELNTRMT 5mm7 K 5.1 BS02 ANP K 1 R85 G86 Q87 G184 T185 G186 K187 T188 H189 N316 Q318 S319 S320 A354 G355 R25 G26 Q27 G124 T125 G126 K127 T128 H129 N256 Q258 S259 S260 A294 G295 ? 0003777,0005524,0007018,0008017 A0A0D1DQH0 31288039 501 NNSNELDRKRSDAGESNIQVVVRVRGQAPNEPKRTAPGILTTSGPRCQQIDVAIEAPQVSSSSAIASTSNLVQESATRQKSYHFDQVFGPEADQGMVYQDVVGPILEEVMSGYNCTIFAYGQTGTGKTHTMEGDLTSQMGTYSSEAGIIPRSLYRLFHTLELSKEDYSVKATFIELYNEELRDLLSIDSSTSSAEPSSSATATKEPQHALRMYDDARGKGVVIQGLEEVALKDAAHGLSVLRRGSQKRQIAATNCNEQSSRSHSVFTMTVFIKDKGSRGEDVLKIGKLNLVDLAGSENIGRSGAENKRAREAGMINQSLLTLGRVINALVEKNSHIPYRESKLTRLLQESLGGRTKTCIIATVSQERANIEETLSTLDYALRAKSIKNRPELNTRMT