5m4k A 2.6 BS01 TF3 A 1 R66 V67 Y129 N142 I143 R58 V59 Y121 N134 I135 H239 E243 K246 N247 H224 E228 K231 N232 2.7.11.2 0004672,0004740,0005515,0005524,0005654,0005739,0005759,0005829,0006006,0006111,0006885,0008286,0010510,0010565,0010906,0016301,0016310,0031670,0034614,0042593,0042803,0045254,0050848,0072332 IC50=2000nM Q15119 28199108 401 GSAPKYIEHFSKFSPSPLSMKQFLDFNACEKTSFTFLRQELPVRLANIMKEINLLPDRVLSTPSVQLVQSWYVQSLLDIMEFLDKDPEDHRTLSQFTDALVTIRNRHNDVVPTMAQGVLEYKDTYGDDPVSNQNIQYFLDRFYLSRISIRMLINQHTLIFDPKHIGSIDPNCNVSEVVKDAYDMAKLLCDKYYMASPDLEIQEINAANSKQPIHMVYVPSHLYHMLFELFKNAMRATVESHESSLILPPIKVMVALGEEDLSIKMSDRGGGVPLRKIERLFSYMYSTAPYGLPISRLYAKYFQGDLQLFSMEGFGTDAVIYLKALSTDSVERLPVY 5m4k A 2.6 BS02 7F9 A 1 N247 R250 A251 D282 V287 T346 N232 R235 A236 D267 V272 T316 H239 E243 K246 N247 H224 E228 K231 N232 2.7.11.2 0004672,0004740,0005515,0005524,0005654,0005739,0005759,0005829,0006006,0006111,0006885,0008286,0010510,0010565,0010906,0016301,0016310,0031670,0034614,0042593,0042803,0045254,0050848,0072332 -logKd/Ki=5.66, Ki=2.17uM IC50=4460nM, Ki=2170nM Q15119 28199108 402 GSAPKYIEHFSKFSPSPLSMKQFLDFNACEKTSFTFLRQELPVRLANIMKEINLLPDRVLSTPSVQLVQSWYVQSLLDIMEFLDKDPEDHRTLSQFTDALVTIRNRHNDVVPTMAQGVLEYKDTYGDDPVSNQNIQYFLDRFYLSRISIRMLINQHTLIFDPKHIGSIDPNCNVSEVVKDAYDMAKLLCDKYYMASPDLEIQEINAANSKQPIHMVYVPSHLYHMLFELFKNAMRATVESHESSLILPPIKVMVALGEEDLSIKMSDRGGGVPLRKIERLFSYMYSTAPYGLPISRLYAKYFQGDLQLFSMEGFGTDAVIYLKALSTDSVERLPVY