5lhh A 3.05 BS01 FAD A 1 G285 G287 S289 E308 A309 R310 G315 R316 G330 A331 V333 V590 L625 P626 W756 S760 Y761 G800 E801 A809 T810 V811 A814 G115 G117 S119 E138 A139 R140 G145 R146 G160 A161 V163 V420 L455 P456 W586 S590 Y591 G630 E631 A639 T640 V641 A644 T335 T165 1.14.99.66 0000122,0000781,0000785,0002039,0002052,0003682,0003713,0005515,0005634,0005654,0005667,0005694,0006325,0006338,0006355,0006357,0006482,0010569,0010718,0010976,0014070,0016491,0019899,0021987,0030374,0031398,0032091,0032451,0032452,0032453,0032454,0032880,0032991,0034644,0036211,0042162,0042551,0042802,0043392,0043426,0043433,0043518,0045793,0045892,0045944,0046098,0050660,0050681,0055001,0060765,0060992,0061629,0061752,0071320,0071480,0090308,0120162,0140297,0140682,0140861,1902166,1990391,1990841,2000179,2000648 O60341 28186757 901 PSGVEGAAFQSRLPHDRMTSQEAACFPDIISGPQQTQKVFLFIRNRTLQLWLDNPKIQLTFEATLQQLEAPYNSDTVLVHRVHSYLERHGLINFGIYKRIKPLPTKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADLGAMVVTGLGGNPMAVVSKQVNMELAKIKQKCPLYEANGQAVPKEKDEMVEQEFNRLLEATSYLSHQLDFNVLNNKPVSLGQALEVVIQLQEKHVKDEQIEHWKKIVKTQEELKELLNKMVNLKEKIKELHQQYKEASEVKPPRDITAEFLVKSKHRDLTALCKEYDELAETQGKLEEKLQELEANPPSDVYLSSRDRQILDWHFANLEFANATPLSTLSLKHWDQDDDFEFTGSHLTVRNGYSCVPVALAEGLDIKLNTAVRQVRYTASGCEVIAVNTRSTSQTFIYKCDAVLCTLPLGVLKQQPPAVQFVPPLPEWKTSAVQRMGFGNLNKVVLCFDRVFWDPSVNLFGHVGSTTASRGELFLFWNLYKAPILLALVAGEAAGIMENISDDVIVGRCLAILKGIFGSSAVPQPKETVVSRWRADPWARGSYSYVAAGSSGNDYDLMAQPITPGPSIPGAPQPIPRLFFAGEHTIRNYPATVHGALLSGLREAGRIADQFLGAMYTL 5lhh A 3.05 BS02 6X0 A 1 V333 Q358 F538 A539 D555 H564 W695 Y761 A809 T810 V163 Q188 F368 A369 D385 H394 W525 Y591 A639 T640 T335 T165 1.14.99.66 0000122,0000781,0000785,0002039,0002052,0003682,0003713,0005515,0005634,0005654,0005667,0005694,0006325,0006338,0006355,0006357,0006482,0010569,0010718,0010976,0014070,0016491,0019899,0021987,0030374,0031398,0032091,0032451,0032452,0032453,0032454,0032880,0032991,0034644,0036211,0042162,0042551,0042802,0043392,0043426,0043433,0043518,0045793,0045892,0045944,0046098,0050660,0050681,0055001,0060765,0060992,0061629,0061752,0071320,0071480,0090308,0120162,0140297,0140682,0140861,1902166,1990391,1990841,2000179,2000648 -logKd/Ki=8.17, IC50=6.7nM IC50=6.7nM O60341 28186757 908 PSGVEGAAFQSRLPHDRMTSQEAACFPDIISGPQQTQKVFLFIRNRTLQLWLDNPKIQLTFEATLQQLEAPYNSDTVLVHRVHSYLERHGLINFGIYKRIKPLPTKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADLGAMVVTGLGGNPMAVVSKQVNMELAKIKQKCPLYEANGQAVPKEKDEMVEQEFNRLLEATSYLSHQLDFNVLNNKPVSLGQALEVVIQLQEKHVKDEQIEHWKKIVKTQEELKELLNKMVNLKEKIKELHQQYKEASEVKPPRDITAEFLVKSKHRDLTALCKEYDELAETQGKLEEKLQELEANPPSDVYLSSRDRQILDWHFANLEFANATPLSTLSLKHWDQDDDFEFTGSHLTVRNGYSCVPVALAEGLDIKLNTAVRQVRYTASGCEVIAVNTRSTSQTFIYKCDAVLCTLPLGVLKQQPPAVQFVPPLPEWKTSAVQRMGFGNLNKVVLCFDRVFWDPSVNLFGHVGSTTASRGELFLFWNLYKAPILLALVAGEAAGIMENISDDVIVGRCLAILKGIFGSSAVPQPKETVVSRWRADPWARGSYSYVAAGSSGNDYDLMAQPITPGPSIPGAPQPIPRLFFAGEHTIRNYPATVHGALLSGLREAGRIADQFLGAMYTL