5lf7 b 2.0 BS01 6V8 b 1 T2 T21 T22 G48 A50 T1 T20 T21 G47 A49 3.4.25.1 0004298,0005839,0051603 P28072 27493187 304 TTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTPIHDRIFCCRSGSAADTQAVADAVTYQLGFHSIELNEPPLVHTAASLFKEMCYRYREDLMAGIIIAGWDPQEGGQVYSVPMGGMMVRQSFAIGGSGSSYIYGYVDATYREGMTKEECLQFTANALALAMERDGSSGGVIRLAAIAESGVERQVLLGDQIPKFAVATLP 5lf7 H 2.0 BS01 MG H 1 I164 D167 S170 I163 D166 S169 T2 D18 R20 K34 G48 S130 D167 S170 T1 D17 R19 K33 G47 S129 D166 S169 3.4.25.1 0004298,0005839,0051603 Q99436 27493187 302 TTIAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDMTTQLISSNLELHSLSTGRLPRVVTANRMLKQMLFRYQGYIGAALVLGGVDVTGPHLYSIYPHGSTDKLPYVTMGSGSLAAMAVFEDKFRPDMEEEEAKNLVSEAIAAGIFNDLGSGSNIDLCVISKNKLDFLRPYTVPNKKGTRLGRYRCEKGTTAVLTEKITPLE 5lf7 H 2.0 BS02 6V8 H 1 T2 A21 T22 E23 A47 G48 T49 A50 T1 A20 T21 E22 A46 G47 T48 A49 T2 D18 R20 K34 G48 S130 D167 S170 T1 D17 R19 K33 G47 S129 D166 S169 3.4.25.1 0004298,0005839,0051603 Q99436 27493187 305 TTIAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDMTTQLISSNLELHSLSTGRLPRVVTANRMLKQMLFRYQGYIGAALVLGGVDVTGPHLYSIYPHGSTDKLPYVTMGSGSLAAMAVFEDKFRPDMEEEEAKNLVSEAIAAGIFNDLGSGSNIDLCVISKNKLDFLRPYTVPNKKGTRLGRYRCEKGTTAVLTEKITPLE 5lf7 I 2.0 BS01 MG I 1 V174 D177 S180 V174 D177 S180 3.4.25.1 0000502,0005515,0005634,0005654,0005737,0005829,0005839,0019774,0043161,0051603,0070062 P49720 27493187 301 SIMSYNGGAVMAMKGKNCVAIAADRRFGIQAQMVTTDFQKIFPMGDRLYIGLAGLATDVQTVAQRLKFRLNLYELKEGRQIKPYTLMSMVANLLYEKRFGPYYTEPVIAGLDPKTFKPFICSLDLIGCPMVTDDFVVSGTCAEQMYGMCESLWEPNMDPDHLFETISQAMLNAVDRDAVSGMGVIVHIIEKDKITTRTLKARMD 5lf7 K 2.0 BS01 MG K 1 T165 D168 A169 S171 T164 D167 A168 S170 T2 D18 R20 K34 G48 S131 D168 S171 T1 D17 R19 K33 G47 S130 D167 S170 3.4.25.1 0004298,0005839,0051603 P28074 27493187 301 TTTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLARQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKRGPGLYYVDSEGNRISGATFSVGSGSVYAYGVMDRGYSYDLEVEQAYDLARRAIYQATYRDAYSGGAVNLYHVREDGWIRVSSDNVADLHEKYS 5lf7 K 2.0 BS02 6V8 K 1 T2 A21 T22 G48 A50 T1 A20 T21 G47 A49 T2 D18 R20 K34 G48 S131 D168 S171 T1 D17 R19 K33 G47 S130 D167 S170 3.4.25.1 0004298,0005839,0051603 IC50=3.4nM P28074 27493187 305 TTTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLARQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKRGPGLYYVDSEGNRISGATFSVGSGSVYAYGVMDRGYSYDLEVEQAYDLARRAIYQATYRDAYSGGAVNLYHVREDGWIRVSSDNVADLHEKYS 5lf7 N 2.0 BS01 6V8 N 1 T2 T21 T22 G48 A50 T1 T20 T21 G47 A49 T2 D18 R20 K34 G48 S131 D168 S171 T1 D17 R19 K33 G47 S130 D167 S170 3.4.25.1 0004298,0005839,0051603 P28072 27493187 305 TTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTPIHDRIFCCRSGSAADTQAVADAVTYQLGFHSIELNEPPLVHTAASLFKEMCYRYREDLMAGIIIAGWDPQEGGQVYSVPMGGMMVRQSFAIGGSGSSYIYGYVDATYREGMTKEECLQFTANALALAMERDGSSGGVIRLAAIAESGVERQVLLGDQIPKFAVATL 5lf7 V 2.0 BS01 MG L 1 I164 D167 S170 I163 D166 S169 T2 D18 R20 K34 G48 S130 D167 S170 T1 D17 R19 K33 G47 S129 D166 S169 3.4.25.1 0004298,0005839,0051603 Q99436 27493187 303 TTIAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDMTTQLISSNLELHSLSTGRLPRVVTANRMLKQMLFRYQGYIGAALVLGGVDVTGPHLYSIYPHGSTDKLPYVTMGSGSLAAMAVFEDKFRPDMEEEEAKNLVSEAIAAGIFNDLGSGSNIDLCVISKNKLDFLRPYTVPNKKGTRLGRYRCEKGTTAVLTEKITPLE 5lf7 V 2.0 BS02 6V8 V 1 T2 A21 T22 E23 A47 G48 A50 T1 A20 T21 E22 A46 G47 A49 T2 D18 R20 K34 G48 S130 D167 S170 T1 D17 R19 K33 G47 S129 D166 S169 3.4.25.1 0004298,0005839,0051603 Q99436 27493187 303 TTIAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDMTTQLISSNLELHSLSTGRLPRVVTANRMLKQMLFRYQGYIGAALVLGGVDVTGPHLYSIYPHGSTDKLPYVTMGSGSLAAMAVFEDKFRPDMEEEEAKNLVSEAIAAGIFNDLGSGSNIDLCVISKNKLDFLRPYTVPNKKGTRLGRYRCEKGTTAVLTEKITPLE 5lf7 W 2.0 BS01 MG W 1 V174 D177 S180 V174 D177 S180 3.4.25.1 0000502,0005515,0005634,0005654,0005737,0005829,0005839,0019774,0043161,0051603,0070062 P49720 27493187 301 SIMSYNGGAVMAMKGKNCVAIAADRRFGIQAQMVTTDFQKIFPMGDRLYIGLAGLATDVQTVAQRLKFRLNLYELKEGRQIKPYTLMSMVANLLYEKRFGPYYTEPVIAGLDPKTFKPFICSLDLIGCPMVTDDFVVSGTCAEQMYGMCESLWEPNMDPDHLFETISQAMLNAVDRDAVSGMGVIVHIIEKDKITTRTLKARMD 5lf7 Y 2.0 BS01 MG I 2 T165 D168 A169 S171 T164 D167 A168 S170 T2 D18 R20 K34 G48 S131 D168 S171 T1 D17 R19 K33 G47 S130 D167 S170 3.4.25.1 0004298,0005839,0051603 P28074 27493187 305 TTTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLARQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKRGPGLYYVDSEGNRISGATFSVGSGSVYAYGVMDRGYSYDLEVEQAYDLARRAIYQATYRDAYSGGAVNLYHVREDGWIRVSSDNVADLHEKYSG 5lf7 Y 2.0 BS02 6V8 Y 1 T2 A21 T22 G48 A50 T1 A20 T21 G47 A49 T2 D18 R20 K34 G48 S131 D168 S171 T1 D17 R19 K33 G47 S130 D167 S170 3.4.25.1 0004298,0005839,0051603 IC50=3.4nM P28074 27493187 306 TTTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLARQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKRGPGLYYVDSEGNRISGATFSVGSGSVYAYGVMDRGYSYDLEVEQAYDLARRAIYQATYRDAYSGGAVNLYHVREDGWIRVSSDNVADLHEKYSG