5k6a A 1.7 BS01 NAP A 1 R14 I15 Y34 H35 N36 S37 D62 L63 N93 A94 S95 T126 L159 D161 K178 G205 S207 L208 R13 I14 Y33 H34 N35 S36 D61 L62 N92 A93 S94 T115 L139 D141 K158 G185 S187 L188 R14 D161 Y174 K178 R13 D141 Y154 K158 ? 0000166,0016491,0047040 O76290 28282886 301 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVKTVETQVAELIGTNAIAPFLLTMSFAQRQSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 5k6a A 1.7 BS02 6QT A 1 S95 F97 Y174 V206 P210 W221 S94 F96 Y154 V186 P190 W201 R14 D161 Y174 K178 R13 D141 Y154 K158 ? 0000166,0016491,0047040 ic50=31uM -logKd/Ki=4.51, IC50=31uM O76290 28282886 302 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVKTVETQVAELIGTNAIAPFLLTMSFAQRQSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 5k6a B 1.7 BS01 NAP B 1 R14 I15 H33 Y34 H35 N36 S37 D62 L63 N93 A94 S95 T126 L159 D161 K178 P204 S207 R13 I14 H32 Y33 H34 N35 S36 D61 L62 N92 A93 S94 T115 L138 D140 K157 P183 S186 R14 D161 Y174 K178 R13 D140 Y153 K157 ? 0000166,0016491,0047040 O76290 28282886 301 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVKTVETQVAELIGTNAIAPFLLTMSFAQRQNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 5k6a B 1.7 BS02 6QT B 1 F97 Y174 W221 F96 Y153 W200 R14 D161 Y174 K178 R13 D140 Y153 K157 ? 0000166,0016491,0047040 ic50=31uM O76290 28282886 302 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVKTVETQVAELIGTNAIAPFLLTMSFAQRQNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 5k6a C 1.7 BS01 NAP C 1 R14 I15 Y34 H35 N36 S37 D62 L63 N93 A94 S95 T126 L159 D161 K178 G205 V206 S207 R13 I14 Y33 H34 N35 S36 D61 L62 N92 A93 S94 T115 L139 D141 K158 G185 V186 S187 R14 D161 Y174 K178 R13 D141 Y154 K158 ? 0000166,0016491,0047040 O76290 28282886 301 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVKTVETQVAELIGTNAIAPFLLTMSFAQRQSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 5k6a C 1.7 BS02 6QT C 1 F97 Y174 V206 W221 F96 Y154 V186 W191 R14 D161 Y174 K178 R13 D141 Y154 K158 ? 0000166,0016491,0047040 ic50=31uM O76290 28282886 302 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVKTVETQVAELIGTNAIAPFLLTMSFAQRQSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 5k6a D 1.7 BS01 NAP D 1 R14 I15 H35 N36 S37 D62 L63 N93 S95 T126 L159 D161 Y174 K178 G205 S207 R13 I14 H34 N35 S36 D61 L62 N92 S94 T115 L139 D141 Y154 K158 G185 S187 R14 D161 Y174 K178 R13 D141 Y154 K158 ? 0000166,0016491,0047040 O76290 28282886 301 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVKTVETQVAELIGTNAIAPFLLTMSFAQRQSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 5k6a D 1.7 BS02 6QT D 1 S95 F97 Y174 V206 P210 W221 S94 F96 Y154 V186 P190 W201 R14 D161 Y174 K178 R13 D141 Y154 K158 ? 0000166,0016491,0047040 ic50=31uM -logKd/Ki=4.51, IC50=31uM O76290 28282886 302 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVKTVETQVAELIGTNAIAPFLLTMSFAQRQSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA