5k5e A 2.8 BS01 6QS A 1 W82 G115 G116 G117 E197 P285 F329 Y332 H438 W80 G113 G114 G115 E195 P283 F327 Y330 H436 G116 G117 G149 S198 A199 Y237 V288 F290 E325 H438 G114 G115 G147 S196 A197 Y235 V286 F288 E323 H436 3.1.1.8 0001540,0003824,0003990,0004104,0005515,0005576,0005615,0005641,0005783,0005788,0005886,0006581,0006805,0007584,0007612,0008285,0009410,0014016,0016486,0016788,0019695,0019899,0033265,0042802,0043279,0050783,0050805,0051384,0051593,0052689,0072562 -logKd/Ki=6.35, IC50=0.443uM IC50=443nM P06276 27405689 609 DIIIATKNGKVRGMNLTVFGGTVTAFLGIPYAQPPLGRLRFKKPQSLTKWSDIWNATKYANSCCQNIDQSFPGFHGSEMWNPNTDLSEDCLYLNVWIPAPKPKNATVLIWIYGGGFQTGTSSLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGNPEAPGNMGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSPGSHSLFTRAILQSGSFNAPWAVTSLYEARNRTLNLAKLTGCSRENETEIIKCLRNKDPQEILLNEAFVVPYGTPLSVNFGPTVDGDFLTDMPDILLELGQFKKTQILVGVNKDEGTAFLVYGAPGFSKDNNSIITRKEFQEGLKIFFPGVSEFGKESILFHYTDWVDDQRPENYREALGDVVGDYNFICPALEFTKKFSEWGNNAFFYYFEHRSSKLPWPEWMGVMHGYEIEFVFGLPLERRDNYTKAEEILSRSIVKRWANFAKYGNPNETQNNSTSWPVFKSTEQKYLTLNTESTRIMTKLRAQQCRFWTSFFPKV 5k5e B 2.8 BS01 6QS B 1 W82 G115 G117 E197 P285 F329 H438 W79 G112 G114 E194 P282 F326 H435 G116 G117 G149 S198 A199 Y237 V288 F290 E325 H438 G113 G114 G146 S195 A196 Y234 V285 F287 E322 H435 3.1.1.8 0001540,0003824,0003990,0004104,0005515,0005576,0005615,0005641,0005783,0005788,0005886,0006581,0006805,0007584,0007612,0008285,0009410,0014016,0016486,0016788,0019695,0019899,0033265,0042802,0043279,0050783,0050805,0051384,0051593,0052689,0072562 IC50=443nM P06276 27405689 609 IIIATKNGKVRGMNLTVFGGTVTAFLGIPYAQPPLGRLRFKKPQSLTKWSDIWNATKYANSCCQNIDQSFPGFHGSEMWNPNTDLSEDCLYLNVWIPAPKPKNATVLIWIYGGGFQTGTSSLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGNPEAPGNMGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSPGSHSLFTRAILQSGSFNAPWAVTSLYEARNRTLNLAKLTGCSRENETEIIKCLRNKDPQEILLNEAFVVPYGTPLSVNFGPTVDGDFLTDMPDILLELGQFKKTQILVGVNKDEGTAFLVYGAPGFSKDNNSIITRKEFQEGLKIFFPGVSEFGKESILFHYTDWVDDQRPENYREALGDVVGDYNFICPALEFTKKFSEWGNNAFFYYFEHRSSKLPWPEWMGVMHGYEIEFVFGLPLERRDNYTKAEEILSRSIVKRWANFAKYGNPNETQNNSTSWPVFKSTEQKYLTLNTESTRIMTKLRAQQCRFWTSFFPKV