5k3l A 2.75 BS01 444 A 1 W317 C320 H323 L324 M365 F388 H479 W53 C56 H59 L60 M101 F124 H215 ? 0003677,0004879,0005634,0006355 IC50=60nM, EC50=54nM, Ki=51nM P51449 900 ASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLCKTHRQSILAKLPPKGKLRSLCSQHVERLQIFQHL 5k3l B 2.75 BS01 444 B 1 W317 C320 H323 M365 F388 I400 H479 W53 C56 H59 M101 F124 I136 H215 ? 0003677,0004879,0005634,0006355 IC50=60nM, EC50=54nM, Ki=51nM P51449 900 ASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLCKTHRQSILAKLPPKGKLRSLCSQHVERLQIFQHLH 5k3l C 2.75 BS01 444 C 1 W317 C320 H323 M365 F378 F388 H479 W53 C56 H59 M101 F114 F124 H215 ? 0003677,0004879,0005634,0006355 IC50=60nM, EC50=54nM, Ki=51nM P51449 900 ASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLCKTHRQSILAKLPPKGKLRSLCSQHVERLQIFQHLH 5k3l D 2.75 BS01 444 D 1 H323 L324 M365 H479 H59 L60 M101 H215 ? 0003677,0004879,0005634,0006355 IC50=60nM, EC50=54nM, Ki=51nM P51449 900 ASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLCKTHRQSILAKLPPKGKLRSLCSQHVERLQIFQHLH