5j6d A 1.9 BS01 FE A 1 H272 H277 E317 H171 H176 E216 H272 H277 E317 S336 H171 H176 E216 S235 1.14.16.4 0004497,0005506,0009072,0016714 P17752 27146606 501 METVPWFPKKISDLDHCANRVLMYGSELDADHPGFKDNVYRKRRKYFADLAMNYKHGDPIPKVEFTEEEIKTWGTVFQELNKLYPTHACREYLKNLPLLSKYCGYREDNIPQLEDVSNFLKERTGFSIRPVAGYLSPRDFLSGLAFRVFHCTQYVRHSSDPFYTPEPDTCHELLGHVPLLAEPSFAQFSQEIGLASLGASEEAVQKLATCYFFTVEFGLCKQDGQLRVFGAGLLSSISELKHALSGHAKVKPFDPKITCKQECLITTFQDVYFVSESFEDAKEKMREFTKTI 5j6d A 1.9 BS02 6H5 A 1 L129 Y235 L236 R257 Y264 T265 P266 P268 H272 A309 Y312 F313 E317 S336 S337 I366 L28 Y134 L135 R156 Y163 T164 P165 P167 H171 A208 Y211 F212 E216 S235 S236 I265 H272 H277 E317 S336 H171 H176 E216 S235 1.14.16.4 0004497,0005506,0009072,0016714 ic50=6nM -logKd/Ki=8.22, IC50=6nM P17752 27146606 504 METVPWFPKKISDLDHCANRVLMYGSELDADHPGFKDNVYRKRRKYFADLAMNYKHGDPIPKVEFTEEEIKTWGTVFQELNKLYPTHACREYLKNLPLLSKYCGYREDNIPQLEDVSNFLKERTGFSIRPVAGYLSPRDFLSGLAFRVFHCTQYVRHSSDPFYTPEPDTCHELLGHVPLLAEPSFAQFSQEIGLASLGASEEAVQKLATCYFFTVEFGLCKQDGQLRVFGAGLLSSISELKHALSGHAKVKPFDPKITCKQECLITTFQDVYFVSESFEDAKEKMREFTKTI 5j6d B 1.9 BS01 6H5 A 1 M102 T104 M1 T3 H272 H277 E317 S336 H142 H147 E187 S200 1.14.16.4 0004497,0005506,0009072,0016714 ic50=6nM P17752 27146606 504 METVPWFPKKISDLDHCANRVLMYGSELDDNVYRKRRKYFADLAMNYKHPIPKVKTWGTVFQELNKLYPTHACREYLKNLPLLLEDVSNFLKERTGFSIRPVAGYLSPRDFLSGLAFRVFHCTQYVRHSSDPFYTPEPDTCHELLGHVPLLAEPSFAQFSQEIGLASLGASEEAVQKLATCYFFTVEFGLCRVFGAGLLSSISELKHALSKVKPFDPKITCKQECLITTFQDVYFFEDAKEKMREFTK 5j6d B 1.9 BS02 FE B 1 H272 H277 E317 H142 H147 E187 H272 H277 E317 S336 H142 H147 E187 S200 1.14.16.4 0004497,0005506,0009072,0016714 P17752 27146606 501 METVPWFPKKISDLDHCANRVLMYGSELDDNVYRKRRKYFADLAMNYKHPIPKVKTWGTVFQELNKLYPTHACREYLKNLPLLLEDVSNFLKERTGFSIRPVAGYLSPRDFLSGLAFRVFHCTQYVRHSSDPFYTPEPDTCHELLGHVPLLAEPSFAQFSQEIGLASLGASEEAVQKLATCYFFTVEFGLCRVFGAGLLSSISELKHALSKVKPFDPKITCKQECLITTFQDVYFFEDAKEKMREFTK 5j6d B 1.9 BS03 6H5 B 1 L129 Y235 L236 R257 Y264 T265 P268 H272 Y312 F313 E317 S336 I366 L28 Y105 L106 R127 Y134 T135 P138 H142 Y182 F183 E187 S200 I227 H272 H277 E317 S336 H142 H147 E187 S200 1.14.16.4 0004497,0005506,0009072,0016714 ic50=6nM P17752 27146606 504 METVPWFPKKISDLDHCANRVLMYGSELDDNVYRKRRKYFADLAMNYKHPIPKVKTWGTVFQELNKLYPTHACREYLKNLPLLLEDVSNFLKERTGFSIRPVAGYLSPRDFLSGLAFRVFHCTQYVRHSSDPFYTPEPDTCHELLGHVPLLAEPSFAQFSQEIGLASLGASEEAVQKLATCYFFTVEFGLCRVFGAGLLSSISELKHALSKVKPFDPKITCKQECLITTFQDVYFFEDAKEKMREFTK