5j1w A 2.42 BS01 6FB A 1 V175 A189 K191 F241 L244 L295 V30 A44 K46 F96 L99 L150 D288 K290 N293 D325 T342 D143 K145 N148 D180 T197 2.7.12.1 0004672,0005524,0006468 ic50=0.19uM -logKd/Ki=6.72, IC50=0.19uM IC50=190nM P49759 27128181 506 SMHLICQSGDVLSARYEIVDTLGEGAFGKVVECIDHKAGGRHVAVKIVKNVDRYCEAARSEIQVLEHLNTTDPNSTFRCVQMLEWFEHHGHICIVFELLGLSTYDFIKENGFLPFRLDHIRKMAYQICKSVNFLHSNKLTHTDLKPENILFVQSDYTEAYNPKIKRDERTLINPDIKVVDFGSATYDDEHHSTLVSTRHYRAPEVILALGWSQPCDVWSIGCILIEYYLGFTVFPTHDSKEHLAMMERILGPLPKHMIQKTRKRKYFHHDRLDWDEHSSAGRYVSRACKPLKEFMLSQDVEHERLFDLIQKMLEYDPAKRITLREALKHPFFDLLKKS 5j1w B 2.42 BS01 6FB B 1 V175 A189 K191 F241 L244 L295 V324 V30 A44 K46 F96 L99 L150 V179 D288 K290 N293 D325 T342 D143 K145 N148 D180 T197 2.7.12.1 0004672,0005524,0006468 ic50=0.19uM IC50=190nM P49759 27128181 503 SMHLICQSGDVLSARYEIVDTLGEGAFGKVVECIDHKAGGRHVAVKIVKNVDRYCEAARSEIQVLEHLNTTDPNSTFRCVQMLEWFEHHGHICIVFELLGLSTYDFIKENGFLPFRLDHIRKMAYQICKSVNFLHSNKLTHTDLKPENILFVQSDYTEAYNPKIKRDERTLINPDIKVVDFGSATYDDEHHSTLVSTRHYRAPEVILALGWSQPCDVWSIGCILIEYYLGFTVFPTHDSKEHLAMMERILGPLPKHMIQKTRKRKYFHHDRLDWDEHSSAGRYVSRACKPLKEFMLSQDVEHERLFDLIQKMLEYDPAKRITLREALKHPFFDLLKK 5j1w C 2.42 BS01 6FB C 1 L167 A189 K191 F241 L244 L295 V324 L22 A44 K46 F96 L99 L150 V179 D288 K290 N293 D325 T342 D143 K145 N148 D180 T197 2.7.12.1 0004672,0005524,0006468 ic50=0.19uM IC50=190nM P49759 27128181 505 SMHLICQSGDVLSARYEIVDTLGEGAFGKVVECIDHKAGGRHVAVKIVKNVDRYCEAARSEIQVLEHLNTTDPNSTFRCVQMLEWFEHHGHICIVFELLGLSTYDFIKENGFLPFRLDHIRKMAYQICKSVNFLHSNKLTHTDLKPENILFVQSDYTEAYNPKIKRDERTLINPDIKVVDFGSATYDDEHHSTLVSTRHYRAPEVILALGWSQPCDVWSIGCILIEYYLGFTVFPTHDSKEHLAMMERILGPLPKHMIQKTRKRKCKPLKEFMLSQDVEHERLFDLIQKMLEYDPAKRITLREALKHPFFDLLKKS 5j1w C 2.42 BS02 6FB C 2 N195 D197 C200 E232 G235 I237 N50 D52 C55 E87 G90 I92 D288 K290 N293 D325 T342 D143 K145 N148 D180 T197 2.7.12.1 0004672,0005524,0006468 ic50=0.19uM IC50=190nM P49759 27128181 506 SMHLICQSGDVLSARYEIVDTLGEGAFGKVVECIDHKAGGRHVAVKIVKNVDRYCEAARSEIQVLEHLNTTDPNSTFRCVQMLEWFEHHGHICIVFELLGLSTYDFIKENGFLPFRLDHIRKMAYQICKSVNFLHSNKLTHTDLKPENILFVQSDYTEAYNPKIKRDERTLINPDIKVVDFGSATYDDEHHSTLVSTRHYRAPEVILALGWSQPCDVWSIGCILIEYYLGFTVFPTHDSKEHLAMMERILGPLPKHMIQKTRKRKCKPLKEFMLSQDVEHERLFDLIQKMLEYDPAKRITLREALKHPFFDLLKKS