5izm A 3.4 BS01 MN A 1 T21 T48 T19 T31 D17 K20 T21 T48 H96 D15 K18 T19 T31 H63 3.6.5.- 0000049,0001514,0003746,0003924,0005525,0005634,0005737,0006412,0016787,0035368,0043021,1990904 P57772 27708257 1001 GRRVNVNVGVLGHIDSGKTALARALSTTAITLDLGFSCFSVPLPARLRSSPLLQVTLVDCPGHASLIRTIIGGAQIIDLMMLVIDVTKGMQTQSAECLVIGQIACQKLVVVLNKIDLLPEGKRQAAIDKMTKKMQKTLENTKFRGAPIIPVAAKPGGAPQGIPELIELLTSQISIPTRDPSGPFLMSVDHCFSIGTVMTGTILSGSISLGDSVEIPALKVVKKVKSMQMFHMPITSAMQGDRLGICVTQFDPKLLERGLVCAPESLHTVHAALISVEKIPYFRGPLQTKAKFHITVGHETVMGRLMFFSPAPDNFDQEPILDSFNFSQEYLFQEQYLSPRQQWALVEFEKPVTCPRLCLVIGSRLDADIHTNTCRLAFHGILLHGLEDRNYADSFLPRLKVYKLKHKDDYSVQLFVGLKVHLSTGELGIIDSFKIHIPGGLLSLTFKRYVFDTHKRMVQS 5izm A 3.4 BS02 GNP A 1 D17 G19 K20 T21 A22 T48 N146 K147 D149 L150 A185 A186 K187 D15 G17 K18 T19 A20 T31 N113 K114 D116 L117 A152 A153 K154 D17 K20 T21 T48 H96 D15 K18 T19 T31 H63 3.6.5.- 0000049,0001514,0003746,0003924,0005525,0005634,0005737,0006412,0016787,0035368,0043021,1990904 -logKd/Ki=5.92, Kd=1.2uM P57772 27708257 1002 GRRVNVNVGVLGHIDSGKTALARALSTTAITLDLGFSCFSVPLPARLRSSPLLQVTLVDCPGHASLIRTIIGGAQIIDLMMLVIDVTKGMQTQSAECLVIGQIACQKLVVVLNKIDLLPEGKRQAAIDKMTKKMQKTLENTKFRGAPIIPVAAKPGGAPQGIPELIELLTSQISIPTRDPSGPFLMSVDHCFSIGTVMTGTILSGSISLGDSVEIPALKVVKKVKSMQMFHMPITSAMQGDRLGICVTQFDPKLLERGLVCAPESLHTVHAALISVEKIPYFRGPLQTKAKFHITVGHETVMGRLMFFSPAPDNFDQEPILDSFNFSQEYLFQEQYLSPRQQWALVEFEKPVTCPRLCLVIGSRLDADIHTNTCRLAFHGILLHGLEDRNYADSFLPRLKVYKLKHKDDYSVQLFVGLKVHLSTGELGIIDSFKIHIPGGLLSLTFKRYVFDTHKRMVQS 5izm B 3.4 BS01 MN B 1 T21 T48 T18 T31 D17 K20 T21 T48 H96 D14 K17 T18 T31 H65 3.6.5.- 0000049,0001514,0003746,0003924,0005525,0005634,0005737,0006412,0016787,0035368,0043021,1990904 P57772 27708257 1001 RRVNVNVGVLGHIDSGKTALARALSTTAGITLDLGFSCFSVPLPARLRSSLEPLLQVTLVDCPGHASLIRTIIGGAQIIDLMMLVIDVTKGMQTQSAECLVIGQIACQKLVVVLNKIDLLPERQAAIDKMTKKMQKTLENTKFRGAPIIPVAAKPGGPQGIPELIELLTSQISIPTRDPSGPFLMSVDHCFSIKGQGTVMTGTILSGSISLGDSVEIPALKVVKKVKSMQMFHMPITSAMQGDRLGICVTQFDPKLLERGLVCAPESLHTVHAALISVEKIPYFRGPLQTKAKFHITVGHETVMGRLMFFSPAPDNFDQEPILDSFNFSQEYLFQEQYLSPRQQWALVEFEKPVTCPRLCLVIGSRLDAHTNTCRLAFHGILLHGLEDRNYADSFLPRLKVYKLKHKHGLVERAMDDYSVIGRSLFETNIQLFVGLKVHLSTGELGIIDSAFGKFKIHIPGGLSPESKKILSQHVVLSLTFKRYVFDTHKRMVQS 5izm B 3.4 BS02 GNP B 1 I16 S18 G19 K20 T21 A22 T48 K147 D149 K187 I13 S15 G16 K17 T18 A19 T31 K116 D118 K154 D17 K20 T21 T48 H96 D14 K17 T18 T31 H65 3.6.5.- 0000049,0001514,0003746,0003924,0005525,0005634,0005737,0006412,0016787,0035368,0043021,1990904 P57772 27708257 1002 RRVNVNVGVLGHIDSGKTALARALSTTAGITLDLGFSCFSVPLPARLRSSLEPLLQVTLVDCPGHASLIRTIIGGAQIIDLMMLVIDVTKGMQTQSAECLVIGQIACQKLVVVLNKIDLLPERQAAIDKMTKKMQKTLENTKFRGAPIIPVAAKPGGPQGIPELIELLTSQISIPTRDPSGPFLMSVDHCFSIKGQGTVMTGTILSGSISLGDSVEIPALKVVKKVKSMQMFHMPITSAMQGDRLGICVTQFDPKLLERGLVCAPESLHTVHAALISVEKIPYFRGPLQTKAKFHITVGHETVMGRLMFFSPAPDNFDQEPILDSFNFSQEYLFQEQYLSPRQQWALVEFEKPVTCPRLCLVIGSRLDAHTNTCRLAFHGILLHGLEDRNYADSFLPRLKVYKLKHKHGLVERAMDDYSVIGRSLFETNIQLFVGLKVHLSTGELGIIDSAFGKFKIHIPGGLSPESKKILSQHVVLSLTFKRYVFDTHKRMVQS