5iu2 A 2.7 BS01 6DA A 1 W132 L134 F149 V152 A165 K167 M207 A209 G210 G213 E217 S257 V260 V269 D270 W56 L58 F72 V75 A88 K90 M130 A132 G133 G136 E140 S180 V183 V192 D193 D253 K255 N258 D270 T290 D176 K178 N181 D193 T213 2.7.11.25 0004672,0005524,0006468 -logKd/Ki=7.80, IC50=0.016uM IC50=16nM P41279 27502541 401 LSSVRYGTVEDLLAFANHISNFYGQRPQESGILLNMVITPQNGRYQIDSDVLLIPWKLTYRNGSDFIPRGAFGKVYLAQDIKTKKRMACKLIPVDQFKPSDVEIQACFRHENIAELYGAVLWGETVHLFMEAGEGGSVLEKLESCGPMREFEIIWVTKHVLKGLDFLHSKKVIHHDIKPSNIVFMSTKAVLVDFGLSVQMTEDVYFPKDLRGTEIYMSPEVILCRGHSTKADIYSLGATLIHMQTGTPPWVKRYPRSAYPSYLYIIHKQAPPLEDIADDCSPGMRELIEASLERNPNHRPRAADLLKHEALN 5iu2 B 2.7 BS01 6DA B 1 W132 L134 G150 V152 A165 K167 M207 A209 G210 G213 E217 S257 V260 V269 D270 W57 L59 G74 V76 A89 K91 M131 A133 G134 G137 E141 S181 V184 V193 D194 D253 K255 N258 D270 T290 D177 K179 N182 D194 T214 2.7.11.25 0004672,0005524,0006468 IC50=16nM P41279 27502541 401 LSSVRYGTVEDLLAFANHISNHFYGQRPQESGILLNMVITPQNGRYQIDSDVLLIPWKLTYRNGSDFIPRGAFGKVYLAQDIKTKKRMACKLIPVDQFKPSDVEIQACFRHENIAELYGAVLWGETVHLFMEAGEGGSVLEKLESCGPMREFEIIWVTKHVLKGLDFLHSKKVIHHDIKPSNIVFMSTKAVLVDFGLSVQMTEDVYFPKDLRGTEIYMSPEVILCRGHSTKADIYSLGATLIHMQTGTPPWVKRYPRSAYPSYLYIIHKQAPPLEDIADDCSPGMRELIEASLERNPNHRPRAADLLKHEALN