5ios A 1.9 BS01 FAD A 1 R78 H79 R80 I81 N169 L173 R174 R76 H77 R78 I79 N167 L171 R172 2.1.1.148 0004799,0006231,0006235,0008168,0009165,0032259,0050660,0050797,0070402 Q9WYT0 27214228 301 HMKIDILDKGFVELVDVMGNDLSAVRAARVSFLKDEERDRHLIEYLMKHGHETPFEHIVFTFHVKAPIFVARQWFRHRIASYNELSGAYSKLSYEFYIPSPERLEGYKTTIPPERVTEKISEIVDKAYRTYLELIESGVPREVARIVLPLNLYTRFFWTVNARSLMNFLNLRADSHAQWEIQQYALAIARIFKEKCPWTFEAFLKYAYKGDILK 5ios A 1.9 BS02 UMP A 1 R74 Q75 R78 R174 R72 Q73 R76 R172 2.1.1.148 0004799,0006231,0006235,0008168,0009165,0032259,0050660,0050797,0070402 Kd=14uM Q9WYT0 27214228 302 HMKIDILDKGFVELVDVMGNDLSAVRAARVSFLKDEERDRHLIEYLMKHGHETPFEHIVFTFHVKAPIFVARQWFRHRIASYNELSGAYSKLSYEFYIPSPERLEGYKTTIPPERVTEKISEIVDKAYRTYLELIESGVPREVARIVLPLNLYTRFFWTVNARSLMNFLNLRADSHAQWEIQQYALAIARIFKEKCPWTFEAFLKYAYKGDILK 5ios A 1.9 BS03 UMP A 2 E86 S88 G89 A90 R147 E84 S86 G87 A88 R145 2.1.1.148 0004799,0006231,0006235,0008168,0009165,0032259,0050660,0050797,0070402 Kd=14uM Q9WYT0 27214228 303 HMKIDILDKGFVELVDVMGNDLSAVRAARVSFLKDEERDRHLIEYLMKHGHETPFEHIVFTFHVKAPIFVARQWFRHRIASYNELSGAYSKLSYEFYIPSPERLEGYKTTIPPERVTEKISEIVDKAYRTYLELIESGVPREVARIVLPLNLYTRFFWTVNARSLMNFLNLRADSHAQWEIQQYALAIARIFKEKCPWTFEAFLKYAYKGDILK 5ios A 1.9 BS04 FAD B 1 N85 E86 N83 E84 2.1.1.148 0004799,0006231,0006235,0008168,0009165,0032259,0050660,0050797,0070402 Q9WYT0 27214228 301 HMKIDILDKGFVELVDVMGNDLSAVRAARVSFLKDEERDRHLIEYLMKHGHETPFEHIVFTFHVKAPIFVARQWFRHRIASYNELSGAYSKLSYEFYIPSPERLEGYKTTIPPERVTEKISEIVDKAYRTYLELIESGVPREVARIVLPLNLYTRFFWTVNARSLMNFLNLRADSHAQWEIQQYALAIARIFKEKCPWTFEAFLKYAYKGDILK 5ios A 1.9 BS05 FAD C 1 S30 T55 E58 I81 N163 R165 S31 T53 E56 I79 N161 R163 2.1.1.148 0004799,0006231,0006235,0008168,0009165,0032259,0050660,0050797,0070402 Q9WYT0 27214228 301 HMKIDILDKGFVELVDVMGNDLSAVRAARVSFLKDEERDRHLIEYLMKHGHETPFEHIVFTFHVKAPIFVARQWFRHRIASYNELSGAYSKLSYEFYIPSPERLEGYKTTIPPERVTEKISEIVDKAYRTYLELIESGVPREVARIVLPLNLYTRFFWTVNARSLMNFLNLRADSHAQWEIQQYALAIARIFKEKCPWTFEAFLKYAYKGDILK 5ios B 1.9 BS01 FAD A 1 N85 E86 N80 E81 2.1.1.148 0004799,0006231,0006235,0008168,0009165,0032259,0050660,0050797,0070402 Q9WYT0 27214228 301 MKIDILDKGFVELVDVMGNDLSAVRAARVSFDEERDRHLIEYLMKHGHETPFEHIVFTFHVKAPIFVARQWFRHRIASYNELSGAYSKLSYEFYIPSPERLEGYKTTIPPERVTEKISEIVDKAYRTYLELIESGVPREVARIVLPLNLYTRFFWTVNARSLMNFLNLRADSHAQWEIQQYALAIARIFKEKCPWTFEAFLKYAYKGDILKEV 5ios B 1.9 BS02 UMP A 1 E86 S88 R147 E81 S83 R142 2.1.1.148 0004799,0006231,0006235,0008168,0009165,0032259,0050660,0050797,0070402 Q9WYT0 27214228 302 MKIDILDKGFVELVDVMGNDLSAVRAARVSFDEERDRHLIEYLMKHGHETPFEHIVFTFHVKAPIFVARQWFRHRIASYNELSGAYSKLSYEFYIPSPERLEGYKTTIPPERVTEKISEIVDKAYRTYLELIESGVPREVARIVLPLNLYTRFFWTVNARSLMNFLNLRADSHAQWEIQQYALAIARIFKEKCPWTFEAFLKYAYKGDILKEV 5ios B 1.9 BS03 UMP A 2 Q75 R78 R174 Q70 R73 R169 2.1.1.148 0004799,0006231,0006235,0008168,0009165,0032259,0050660,0050797,0070402 Q9WYT0 27214228 303 MKIDILDKGFVELVDVMGNDLSAVRAARVSFDEERDRHLIEYLMKHGHETPFEHIVFTFHVKAPIFVARQWFRHRIASYNELSGAYSKLSYEFYIPSPERLEGYKTTIPPERVTEKISEIVDKAYRTYLELIESGVPREVARIVLPLNLYTRFFWTVNARSLMNFLNLRADSHAQWEIQQYALAIARIFKEKCPWTFEAFLKYAYKGDILKEV 5ios B 1.9 BS04 FAD B 1 R78 H79 R80 I81 N169 L173 R174 H178 R73 H74 R75 I76 N164 L168 R169 H173 2.1.1.148 0004799,0006231,0006235,0008168,0009165,0032259,0050660,0050797,0070402 Q9WYT0 27214228 301 MKIDILDKGFVELVDVMGNDLSAVRAARVSFDEERDRHLIEYLMKHGHETPFEHIVFTFHVKAPIFVARQWFRHRIASYNELSGAYSKLSYEFYIPSPERLEGYKTTIPPERVTEKISEIVDKAYRTYLELIESGVPREVARIVLPLNLYTRFFWTVNARSLMNFLNLRADSHAQWEIQQYALAIARIFKEKCPWTFEAFLKYAYKGDILKEV 5ios B 1.9 BS05 FAD D 1 T55 E58 I81 N163 R165 T50 E53 I76 N158 R160 2.1.1.148 0004799,0006231,0006235,0008168,0009165,0032259,0050660,0050797,0070402 Q9WYT0 27214228 301 MKIDILDKGFVELVDVMGNDLSAVRAARVSFDEERDRHLIEYLMKHGHETPFEHIVFTFHVKAPIFVARQWFRHRIASYNELSGAYSKLSYEFYIPSPERLEGYKTTIPPERVTEKISEIVDKAYRTYLELIESGVPREVARIVLPLNLYTRFFWTVNARSLMNFLNLRADSHAQWEIQQYALAIARIFKEKCPWTFEAFLKYAYKGDILKEV 5ios C 1.9 BS01 FAD A 1 T55 E58 I81 N163 R165 T50 E53 I76 N158 R160 2.1.1.148 0004799,0006231,0006235,0008168,0009165,0032259,0050660,0050797,0070402 Q9WYT0 27214228 301 MKIDILDKGFVELVDVMGNDLSAVRAARVSKDEERDRHLIEYLMKHGHETPFEHIVFTFHVKAPIFVARQWFRHRIASYNELSGAYSKLSYEFYIPSPERLEGYKTTIPPERVTEKISEIVDKAYRTYLELIESGVPREVARIVLPLNLYTRFFWTVNARSLMNFLNLRADSHAQWEIQQYALAIARIFKEKCPWTFEAFLKYAYKGDILKEV 5ios C 1.9 BS02 FAD C 1 R78 H79 R80 I81 N169 L173 R174 H178 R73 H74 R75 I76 N164 L168 R169 H173 2.1.1.148 0004799,0006231,0006235,0008168,0009165,0032259,0050660,0050797,0070402 Q9WYT0 27214228 301 MKIDILDKGFVELVDVMGNDLSAVRAARVSKDEERDRHLIEYLMKHGHETPFEHIVFTFHVKAPIFVARQWFRHRIASYNELSGAYSKLSYEFYIPSPERLEGYKTTIPPERVTEKISEIVDKAYRTYLELIESGVPREVARIVLPLNLYTRFFWTVNARSLMNFLNLRADSHAQWEIQQYALAIARIFKEKCPWTFEAFLKYAYKGDILKEV 5ios C 1.9 BS03 UMP C 1 E86 S88 R147 E81 S83 R142 2.1.1.148 0004799,0006231,0006235,0008168,0009165,0032259,0050660,0050797,0070402 Kd=14uM Q9WYT0 27214228 302 MKIDILDKGFVELVDVMGNDLSAVRAARVSKDEERDRHLIEYLMKHGHETPFEHIVFTFHVKAPIFVARQWFRHRIASYNELSGAYSKLSYEFYIPSPERLEGYKTTIPPERVTEKISEIVDKAYRTYLELIESGVPREVARIVLPLNLYTRFFWTVNARSLMNFLNLRADSHAQWEIQQYALAIARIFKEKCPWTFEAFLKYAYKGDILKEV 5ios C 1.9 BS04 FAD D 1 N85 E86 N80 E81 2.1.1.148 0004799,0006231,0006235,0008168,0009165,0032259,0050660,0050797,0070402 Q9WYT0 27214228 301 MKIDILDKGFVELVDVMGNDLSAVRAARVSKDEERDRHLIEYLMKHGHETPFEHIVFTFHVKAPIFVARQWFRHRIASYNELSGAYSKLSYEFYIPSPERLEGYKTTIPPERVTEKISEIVDKAYRTYLELIESGVPREVARIVLPLNLYTRFFWTVNARSLMNFLNLRADSHAQWEIQQYALAIARIFKEKCPWTFEAFLKYAYKGDILKEV 5ios C 1.9 BS05 UMP D 1 Q75 R78 R174 Q70 R73 R169 2.1.1.148 0004799,0006231,0006235,0008168,0009165,0032259,0050660,0050797,0070402 Kd=14uM Q9WYT0 27214228 302 MKIDILDKGFVELVDVMGNDLSAVRAARVSKDEERDRHLIEYLMKHGHETPFEHIVFTFHVKAPIFVARQWFRHRIASYNELSGAYSKLSYEFYIPSPERLEGYKTTIPPERVTEKISEIVDKAYRTYLELIESGVPREVARIVLPLNLYTRFFWTVNARSLMNFLNLRADSHAQWEIQQYALAIARIFKEKCPWTFEAFLKYAYKGDILKEV 5ios D 1.9 BS01 FAD B 1 S30 T55 E58 I81 N163 R165 S30 T54 E57 I80 N162 R164 2.1.1.148 0004799,0006231,0006235,0008168,0009165,0032259,0050660,0050797,0070402 Q9WYT0 27214228 301 MKIDILDKGFVELVDVMGNDLSAVRAARVSFDMLKDEERDRHLIEYLMKHGHETPFEHIVFTFHVKAPIFVARQWFRHRIASYNELSGAYSKLSYEFYIPSPERLEGYKTTIPPERVTEKISEIVDKAYRTYLELIESGVPREVARIVLPLNLYTRFFWTVNARSLMNFLNLRADSHAQWEIQQYALAIARIFKEKCPWTFEAFLKYAYKGDILKEV 5ios D 1.9 BS02 FAD C 1 N85 E86 N84 E85 2.1.1.148 0004799,0006231,0006235,0008168,0009165,0032259,0050660,0050797,0070402 Q9WYT0 27214228 301 MKIDILDKGFVELVDVMGNDLSAVRAARVSFDMLKDEERDRHLIEYLMKHGHETPFEHIVFTFHVKAPIFVARQWFRHRIASYNELSGAYSKLSYEFYIPSPERLEGYKTTIPPERVTEKISEIVDKAYRTYLELIESGVPREVARIVLPLNLYTRFFWTVNARSLMNFLNLRADSHAQWEIQQYALAIARIFKEKCPWTFEAFLKYAYKGDILKEV 5ios D 1.9 BS03 UMP C 1 R74 Q75 R78 R174 R73 Q74 R77 R173 2.1.1.148 0004799,0006231,0006235,0008168,0009165,0032259,0050660,0050797,0070402 Kd=14uM Q9WYT0 27214228 302 MKIDILDKGFVELVDVMGNDLSAVRAARVSFDMLKDEERDRHLIEYLMKHGHETPFEHIVFTFHVKAPIFVARQWFRHRIASYNELSGAYSKLSYEFYIPSPERLEGYKTTIPPERVTEKISEIVDKAYRTYLELIESGVPREVARIVLPLNLYTRFFWTVNARSLMNFLNLRADSHAQWEIQQYALAIARIFKEKCPWTFEAFLKYAYKGDILKEV 5ios D 1.9 BS04 FAD D 1 R78 H79 R80 I81 N169 L173 R174 H178 R77 H78 R79 I80 N168 L172 R173 H177 2.1.1.148 0004799,0006231,0006235,0008168,0009165,0032259,0050660,0050797,0070402 Q9WYT0 27214228 301 MKIDILDKGFVELVDVMGNDLSAVRAARVSFDMLKDEERDRHLIEYLMKHGHETPFEHIVFTFHVKAPIFVARQWFRHRIASYNELSGAYSKLSYEFYIPSPERLEGYKTTIPPERVTEKISEIVDKAYRTYLELIESGVPREVARIVLPLNLYTRFFWTVNARSLMNFLNLRADSHAQWEIQQYALAIARIFKEKCPWTFEAFLKYAYKGDILKEV 5ios D 1.9 BS05 UMP D 1 E86 S88 G89 A90 R147 E85 S87 G88 A89 R146 2.1.1.148 0004799,0006231,0006235,0008168,0009165,0032259,0050660,0050797,0070402 Kd=14uM Q9WYT0 27214228 302 MKIDILDKGFVELVDVMGNDLSAVRAARVSFDMLKDEERDRHLIEYLMKHGHETPFEHIVFTFHVKAPIFVARQWFRHRIASYNELSGAYSKLSYEFYIPSPERLEGYKTTIPPERVTEKISEIVDKAYRTYLELIESGVPREVARIVLPLNLYTRFFWTVNARSLMNFLNLRADSHAQWEIQQYALAIARIFKEKCPWTFEAFLKYAYKGDILKEV