5i60 A 2.12 BS01 PLP A 1 R99 R192 K202 Y207 E237 T240 M241 L266 G268 V269 V270 T313 R93 R186 K196 Y201 E231 T234 M235 L260 G262 V263 V264 T307 K202 K196 2.6.1.42 0003824,0004084,0005515,0005654,0005739,0005759,0006549,0006550,0006551,0006573,0006629,0008483,0008652,0009081,0009082,0009083,0009098,0009099,0010817,0050048,0052654,0052655,0052656,1990830 O15382 26938474 401 SSFKAADLQLEMTQKPHKKPPLVFGKTFTDHMLMVEWNDKGWGQPRIQPFQNLTLHPASSSLHYSLQLFEGMKAFKGKDQQVRLFRPWLNMDRMLRSAMRLCLPSFDKLELLECIRRLIEVDKDWVPDAAGTSLYVRPVLIGNEPSLGVSQPTRALLFVILCPVGAYFPGGSVTPVSLLADPAFIRAWVGGVGNYKLGGNYGPTVLVQQEALKRGCEQVLWLYGPDHQLTEVGTMNIFVYWTHEDGVLELVTPPLNGVILPGVVRQSLLDMAQTWGEFRVVERTITMKQLLRALEEGRVREVFGSGTACQVCPVHRILYKDRNLHIPTMENGPELILRFQKELKEIQYGIRAHEWMFPV 5i60 A 2.12 BS02 67W A 1 F30 Y141 G171 Y173 T240 G312 A314 F24 Y135 G165 Y167 T234 G306 A308 K202 K196 2.6.1.42 0003824,0004084,0005515,0005654,0005739,0005759,0006549,0006550,0006551,0006573,0006629,0008483,0008652,0009081,0009082,0009083,0009098,0009099,0010817,0050048,0052654,0052655,0052656,1990830 ic50=0.00000001M IC50=1995nM O15382 26938474 402 SSFKAADLQLEMTQKPHKKPPLVFGKTFTDHMLMVEWNDKGWGQPRIQPFQNLTLHPASSSLHYSLQLFEGMKAFKGKDQQVRLFRPWLNMDRMLRSAMRLCLPSFDKLELLECIRRLIEVDKDWVPDAAGTSLYVRPVLIGNEPSLGVSQPTRALLFVILCPVGAYFPGGSVTPVSLLADPAFIRAWVGGVGNYKLGGNYGPTVLVQQEALKRGCEQVLWLYGPDHQLTEVGTMNIFVYWTHEDGVLELVTPPLNGVILPGVVRQSLLDMAQTWGEFRVVERTITMKQLLRALEEGRVREVFGSGTACQVCPVHRILYKDRNLHIPTMENGPELILRFQKELKEIQYGIRAHEWMFPV 5i60 B 2.12 BS01 PLP B 1 R99 K202 Y207 E237 T240 M241 L266 G268 V269 V270 T313 R91 K194 Y199 E229 T232 M233 L258 G260 V261 V262 T305 K202 K194 2.6.1.42 0003824,0004084,0005515,0005654,0005739,0005759,0006549,0006550,0006551,0006573,0006629,0008483,0008652,0009081,0009082,0009083,0009098,0009099,0010817,0050048,0052654,0052655,0052656,1990830 O15382 26938474 401 SSFKAADLQLEMTQKPHKKPVFGKTFTDHMLMVEWNDKGWGQPRIQPFQNLTLHPASSSLHYSLQLFEGMKAFKGKDQQVRLFRPWLNMDRMLRSAMRLCLPSFDKLELLECIRRLIEVDKDWVPDAAGTSLYVRPVLIGNEPSLGVSQPTRALLFVILCPVGAYFPGGSVTPVSLLADPAFIRAWVGGVGNYKLGGNYGPTVLVQQEALKRGCEQVLWLYGPDHQLTEVGTMNIFVYWTHEDGVLELVTPPLNGVILPGVVRQSLLDMAQTWGEFRVVERTITMKQLLRALEEGRVREVFGSGTACQVCPVHRILYKDRNLHIPTMENGPELILRFQKELKEIQYGIRAHEWMFPV 5i60 B 2.12 BS02 67W B 1 F30 G171 Y173 T240 G312 A314 F22 G163 Y165 T232 G304 A306 K202 K194 2.6.1.42 0003824,0004084,0005515,0005654,0005739,0005759,0006549,0006550,0006551,0006573,0006629,0008483,0008652,0009081,0009082,0009083,0009098,0009099,0010817,0050048,0052654,0052655,0052656,1990830 ic50=0.00000001M IC50=1995nM O15382 26938474 402 SSFKAADLQLEMTQKPHKKPVFGKTFTDHMLMVEWNDKGWGQPRIQPFQNLTLHPASSSLHYSLQLFEGMKAFKGKDQQVRLFRPWLNMDRMLRSAMRLCLPSFDKLELLECIRRLIEVDKDWVPDAAGTSLYVRPVLIGNEPSLGVSQPTRALLFVILCPVGAYFPGGSVTPVSLLADPAFIRAWVGGVGNYKLGGNYGPTVLVQQEALKRGCEQVLWLYGPDHQLTEVGTMNIFVYWTHEDGVLELVTPPLNGVILPGVVRQSLLDMAQTWGEFRVVERTITMKQLLRALEEGRVREVFGSGTACQVCPVHRILYKDRNLHIPTMENGPELILRFQKELKEIQYGIRAHEWMFPV