5hk2 A 3.2 BS01 61V A 1 M93 L105 F107 S117 Y120 D126 H154 E172 Y206 M92 L104 F106 S116 Y119 D125 H153 E171 Y205 ? 0004985,0005515,0005634,0005635,0005637,0005640,0005783,0005789,0005811,0005829,0005886,0006869,0007399,0014069,0016020,0030426,0031410,0038003,0038023,0042995,0043523,0045202,0045211,0070161,0070207,0098794,0098839,0098978,0150052 -logKd/Ki=8.59, Ki=2.6nM Ki=1.7nM Q99720 27042935 301 QWAVGRRWAWAALLLAVAAVLTQVVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSRLIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSRGHSGRYWAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPSTLAFALADTVFSTQDFLTLFYTLRSYARGLRLELTTYL 5hk2 B 3.2 BS01 61V B 1 V78 W83 M87 F101 Y114 D120 E166 L176 A179 Y200 V76 W81 M85 F99 Y112 D118 E164 L174 A177 Y198 ? 0004985,0005515,0005634,0005635,0005637,0005640,0005783,0005789,0005811,0005829,0005886,0006869,0007399,0014069,0016020,0030426,0031410,0038003,0038023,0042995,0043523,0045202,0045211,0070161,0070207,0098794,0098839,0098978,0150052 Ki=1.7nM Q99720 27042935 301 WAVGRLLLAVAAVLTQVVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSRLIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSRGHSGRYWAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPSTLAFALADTVFSTQDFLTLFYTLRSYARGLRLELTTYLFG 5hk2 C 3.2 BS01 61V C 1 V84 M93 F107 Y120 D126 E172 T181 L182 A185 Y206 V77 M86 F100 Y113 D119 E165 T174 L175 A178 Y199 ? 0004985,0005515,0005634,0005635,0005637,0005640,0005783,0005789,0005811,0005829,0005886,0006869,0007399,0014069,0016020,0030426,0031410,0038003,0038023,0042995,0043523,0045202,0045211,0070161,0070207,0098794,0098839,0098978,0150052 Ki=1.7nM Q99720 27042935 301 RWAWAALLLAVAAVLTQVVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSRLIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSRGHSGRYWAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPSTLAFALADTVFSTQDFLTLFYTLRSYARGLRLELTTYLF