5g0w A 1.79 BS01 NAD A 1 G14 I16 S20 I21 F41 L63 D64 V65 S94 I95 I122 M147 D148 F149 K165 A191 P193 I194 T196 G13 I15 S19 I20 F40 L62 D63 V64 S93 I94 I121 M146 D147 F148 K164 A190 P192 I193 T195 Y158 K165 Y157 K164 1.3.1.9 0004318,0005504,0005886,0006633,0009274,0016491,0030497,0046677,0050343,0070403,0071768 P9WGR1 27864515 1270 TGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 5g0w A 1.79 BS02 MG A 1 D223 Q224 A226 D222 Q223 A225 Y158 K165 Y157 K164 1.3.1.9 0004318,0005504,0005886,0006633,0009274,0016491,0030497,0046677,0050343,0070403,0071768 P9WGR1 27864515 1271 TGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 5g0w B 1.79 BS01 NAD B 1 G14 I16 S20 I21 F41 D64 V65 S94 I95 G96 I122 M147 D148 F149 K165 A191 P193 I194 T196 G13 I15 S19 I20 F40 D63 V64 S93 I94 G95 I121 M146 D147 F148 K164 A190 P192 I193 T195 Y158 K165 Y157 K164 1.3.1.9 0004318,0005504,0005886,0006633,0009274,0016491,0030497,0046677,0050343,0070403,0071768 P9WGR1 27864515 1270 TGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 5g0w B 1.79 BS02 9NU B 1 I16 F41 R43 F97 M98 M103 A198 M199 I15 F40 R42 F96 M97 M102 A197 M198 Y158 K165 Y157 K164 1.3.1.9 0004318,0005504,0005886,0006633,0009274,0016491,0030497,0046677,0050343,0070403,0071768 ic50=16.3uM Kd=49000nM, IC50=12000nM P9WGR1 27864515 1271 TGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 5g0w C 1.79 BS01 NAD C 1 G14 I16 S20 I21 F41 D64 V65 S94 I95 G96 I122 M147 D148 F149 K165 P193 I194 T196 G13 I15 S19 I20 F40 D63 V64 S93 I94 G95 I121 M146 D147 F148 K164 P192 I193 T195 Y158 K165 Y157 K164 1.3.1.9 0004318,0005504,0005886,0006633,0009274,0016491,0030497,0046677,0050343,0070403,0071768 P9WGR1 27864515 1270 TGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 5g0w C 1.79 BS02 9NU C 1 I16 F41 F97 M98 M103 Y158 I15 F40 F96 M97 M102 Y157 Y158 K165 Y157 K164 1.3.1.9 0004318,0005504,0005886,0006633,0009274,0016491,0030497,0046677,0050343,0070403,0071768 ic50=16.3uM Kd=49000nM, IC50=12000nM P9WGR1 27864515 1271 TGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 5g0w D 1.79 BS01 NAD D 1 G14 I16 S20 I21 F41 D64 V65 S94 I95 G96 I122 M147 D148 F149 K165 A191 P193 I194 T196 G12 I14 S18 I19 F39 D59 V60 S89 I90 G91 I117 M142 D143 F144 K160 A186 P188 I189 T191 Y158 K165 Y153 K160 1.3.1.9 0004318,0005504,0005886,0006633,0009274,0016491,0030497,0046677,0050343,0070403,0071768 P9WGR1 27864515 1270 GLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 5g0w D 1.79 BS02 MG D 1 D223 Q224 A226 D218 Q219 A221 Y158 K165 Y153 K160 1.3.1.9 0004318,0005504,0005886,0006633,0009274,0016491,0030497,0046677,0050343,0070403,0071768 P9WGR1 27864515 1271 GLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 5g0w D 1.79 BS03 MG D 2 G141 D248 G136 D243 Y158 K165 Y153 K160 1.3.1.9 0004318,0005504,0005886,0006633,0009274,0016491,0030497,0046677,0050343,0070403,0071768 P9WGR1 27864515 1272 GLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL