5fct A 1.55 BS01 UFP A 1 R44 C189 Q208 R209 S210 D212 N220 H250 Y252 R24 C169 Q188 R189 S190 D192 N200 H230 Y232 E81 W103 Y129 C189 R209 D212 E61 W83 Y109 C169 R189 D192 2.1.1.45 0000900,0003729,0004799,0005542,0005634,0005737,0005739,0005743,0005759,0006206,0006231,0006235,0006417,0007623,0008168,0009165,0009410,0009636,0014070,0016741,0017148,0019860,0032259,0032570,0033189,0034097,0035999,0042803,0045471,0046653,0046683,0048589,0051216,0051384,0051593,0060574,0097421,1901363,1990825 Ki=20nM, IC50=>10000nM P07607 401 RHGELQYLRQVEHILRCGFKKEDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVRIWDANGSRDFLDSLGFSARQEGDLGPVYGFQWRHFGAEYKDMDSDYSGQGVDQLQKVIDTIKTNPDDRRIIMCAWNPKDLPLMALPPCHALCQFYVVNGELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLQPGDFVHTLGDAHIYLNHIEPLKIQLQREPRPFPKLKILRKVETIDDFKVEDFQIEGYNPHPTIKMEMAV 5fct A 1.55 BS02 C2F A 1 F74 I102 W103 N106 L186 D212 L215 G216 A306 F54 I82 W83 N86 L166 D192 L195 G196 A286 E81 W103 Y129 C189 R209 D212 E61 W83 Y109 C169 R189 D192 2.1.1.45 0000900,0003729,0004799,0005542,0005634,0005737,0005739,0005743,0005759,0006206,0006231,0006235,0006417,0007623,0008168,0009165,0009410,0009636,0014070,0016741,0017148,0019860,0032259,0032570,0033189,0034097,0035999,0042803,0045471,0046653,0046683,0048589,0051216,0051384,0051593,0060574,0097421,1901363,1990825 P07607 402 RHGELQYLRQVEHILRCGFKKEDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVRIWDANGSRDFLDSLGFSARQEGDLGPVYGFQWRHFGAEYKDMDSDYSGQGVDQLQKVIDTIKTNPDDRRIIMCAWNPKDLPLMALPPCHALCQFYVVNGELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLQPGDFVHTLGDAHIYLNHIEPLKIQLQREPRPFPKLKILRKVETIDDFKVEDFQIEGYNPHPTIKMEMAV 5fct A 1.55 BS03 UFP B 1 R169 R170 R149 R150 E81 W103 Y129 C189 R209 D212 E61 W83 Y109 C169 R189 D192 2.1.1.45 0000900,0003729,0004799,0005542,0005634,0005737,0005739,0005743,0005759,0006206,0006231,0006235,0006417,0007623,0008168,0009165,0009410,0009636,0014070,0016741,0017148,0019860,0032259,0032570,0033189,0034097,0035999,0042803,0045471,0046653,0046683,0048589,0051216,0051384,0051593,0060574,0097421,1901363,1990825 Ki=20nM, IC50=>10000nM P07607 401 RHGELQYLRQVEHILRCGFKKEDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVRIWDANGSRDFLDSLGFSARQEGDLGPVYGFQWRHFGAEYKDMDSDYSGQGVDQLQKVIDTIKTNPDDRRIIMCAWNPKDLPLMALPPCHALCQFYVVNGELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLQPGDFVHTLGDAHIYLNHIEPLKIQLQREPRPFPKLKILRKVETIDDFKVEDFQIEGYNPHPTIKMEMAV 5fct B 1.55 BS01 UFP A 1 R169 R170 R149 R150 E81 W103 Y129 C189 R209 D212 E61 W83 Y109 C169 R189 D192 2.1.1.45 0000900,0003729,0004799,0005542,0005634,0005737,0005739,0005743,0005759,0006206,0006231,0006235,0006417,0007623,0008168,0009165,0009410,0009636,0014070,0016741,0017148,0019860,0032259,0032570,0033189,0034097,0035999,0042803,0045471,0046653,0046683,0048589,0051216,0051384,0051593,0060574,0097421,1901363,1990825 Ki=20nM, IC50=>10000nM P07607 401 RHGELQYLRQVEHILRCGFKKEDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVRIWDANGSRDFLDSLGFSARQEGDLGPVYGFQWRHFGAEYKDMDSDYSGQGVDQLQKVIDTIKTNPDDRRIIMCAWNPKDLPLMALPPCHALCQFYVVNGELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLQPGDFVHTLGDAHIYLNHIEPLKIQLQREPRPFPKLKILRKVETIDDFKVEDFQIEGYNPHPTIKMEMAV 5fct B 1.55 BS02 UFP B 1 R44 C189 Q208 R209 S210 D212 N220 H250 Y252 R24 C169 Q188 R189 S190 D192 N200 H230 Y232 E81 W103 Y129 C189 R209 D212 E61 W83 Y109 C169 R189 D192 2.1.1.45 0000900,0003729,0004799,0005542,0005634,0005737,0005739,0005743,0005759,0006206,0006231,0006235,0006417,0007623,0008168,0009165,0009410,0009636,0014070,0016741,0017148,0019860,0032259,0032570,0033189,0034097,0035999,0042803,0045471,0046653,0046683,0048589,0051216,0051384,0051593,0060574,0097421,1901363,1990825 Ki=20nM, IC50=>10000nM P07607 401 RHGELQYLRQVEHILRCGFKKEDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVRIWDANGSRDFLDSLGFSARQEGDLGPVYGFQWRHFGAEYKDMDSDYSGQGVDQLQKVIDTIKTNPDDRRIIMCAWNPKDLPLMALPPCHALCQFYVVNGELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLQPGDFVHTLGDAHIYLNHIEPLKIQLQREPRPFPKLKILRKVETIDDFKVEDFQIEGYNPHPTIKMEMAV 5fct B 1.55 BS03 C2F B 1 V73 F74 I102 W103 N106 L186 D212 L215 G216 F219 M305 A306 V53 F54 I82 W83 N86 L166 D192 L195 G196 F199 M285 A286 E81 W103 Y129 C189 R209 D212 E61 W83 Y109 C169 R189 D192 2.1.1.45 0000900,0003729,0004799,0005542,0005634,0005737,0005739,0005743,0005759,0006206,0006231,0006235,0006417,0007623,0008168,0009165,0009410,0009636,0014070,0016741,0017148,0019860,0032259,0032570,0033189,0034097,0035999,0042803,0045471,0046653,0046683,0048589,0051216,0051384,0051593,0060574,0097421,1901363,1990825 P07607 402 RHGELQYLRQVEHILRCGFKKEDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVRIWDANGSRDFLDSLGFSARQEGDLGPVYGFQWRHFGAEYKDMDSDYSGQGVDQLQKVIDTIKTNPDDRRIIMCAWNPKDLPLMALPPCHALCQFYVVNGELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLQPGDFVHTLGDAHIYLNHIEPLKIQLQREPRPFPKLKILRKVETIDDFKVEDFQIEGYNPHPTIKMEMAV