5fbn C 1.8 BS01 5WF C 1 L408 V416 A428 K430 F442 M449 L460 I472 T474 M477 C481 N484 L528 S538 D539 F540 L542 L14 V22 A34 K36 F48 M55 L66 I78 T80 M83 C87 N90 L134 S144 D145 F146 L148 N526 D539 N132 D145 2.7.10.2 0004672,0004713,0005524,0006468 ic50=0.27nM -logKd/Ki=9.57, IC50=0.27nM IC50=8.0nM, EC50=<10.00nM Q06187 26985298 701 WEIDPKDLTFLKELGTGQFGVVKYGKWRGQYDVAIKMIKEGSMSEDEFIEEAKVMMNLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRHRFQTQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLYRPHLASEKVYTIMYSCWHEKADERPTFKILLSNILDVMDEE 5fbn C 1.8 BS02 5WE C 1 W421 Y425 S453 Y461 W27 Y31 S59 Y67 N526 D539 N132 D145 2.7.10.2 0004672,0004713,0005524,0006468 Q06187 26985298 702 WEIDPKDLTFLKELGTGQFGVVKYGKWRGQYDVAIKMIKEGSMSEDEFIEEAKVMMNLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRHRFQTQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLYRPHLASEKVYTIMYSCWHEKADERPTFKILLSNILDVMDEE 5fbn D 1.8 BS01 5WF D 1 L408 T410 V416 A428 K430 F442 M449 L460 I472 T474 M477 G480 C481 N484 L528 S538 D539 F540 L542 L15 T17 V23 A35 K37 F49 M56 L67 I79 T81 M84 G87 C88 N91 L135 S145 D146 F147 L149 N526 D539 N133 D146 2.7.10.2 0004672,0004713,0005524,0006468 ic50=0.27nM IC50=8.0nM, EC50=<10.00nM Q06187 26985298 702 SWEIDPKDLTFLKELGTGQFGVVKYGKWRGQYDVAIKMIKEGSMSEDEFIEEAKVMMNLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRHRFQTQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLYRPHLASEKVYTIMYSCWHEKADERPTFKILLSNILDVMDEE 5fbn D 1.8 BS02 5WE D 1 W421 Y425 S453 Q459 Y461 W28 Y32 S60 Q66 Y68 N526 D539 N133 D146 2.7.10.2 0004672,0004713,0005524,0006468 Q06187 26985298 703 SWEIDPKDLTFLKELGTGQFGVVKYGKWRGQYDVAIKMIKEGSMSEDEFIEEAKVMMNLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRHRFQTQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLYRPHLASEKVYTIMYSCWHEKADERPTFKILLSNILDVMDEE 5fbn D 1.8 BS03 5WE D 2 R618 E624 Y627 T628 Y631 R215 E221 Y224 T225 Y228 N526 D539 N133 D146 2.7.10.2 0004672,0004713,0005524,0006468 Q06187 26985298 705 SWEIDPKDLTFLKELGTGQFGVVKYGKWRGQYDVAIKMIKEGSMSEDEFIEEAKVMMNLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRHRFQTQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLYRPHLASEKVYTIMYSCWHEKADERPTFKILLSNILDVMDEE