5f94 A 2.51 BS01 3UO A 1 A83 K85 Y134 V135 R141 L188 D200 A48 K50 Y99 V100 R106 L153 D165 D181 K183 N186 D200 S219 D146 K148 N151 D165 S184 2.7.11.1,2.7.11.26 0004672,0005524,0006468 -logKd/Ki=8.47, IC50=3.4nM IC50=3.4nM P49841 26751161 401 KVTTVVATPGQGPDRPQEVSYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHPWTKVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELRDPNVKLPNGRDTPALFNFTTQELSSNPPLATILIPPH 5f94 B 2.51 BS01 3UO B 1 A83 K85 L132 Y134 V135 L188 C199 D200 A47 K49 L96 Y98 V99 L152 C163 D164 D181 K183 N186 D200 S219 D145 K147 N150 D164 S183 2.7.11.1,2.7.11.26 0004672,0005524,0006468 IC50=3.4nM P49841 26751161 401 VTTVVATPGQGPDRPQEVSYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHPWTKVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELRDPNVKLPNGRDTPALFNFTTQELSSNPPLATILIPPHARIQ