5etx A 2.35 BS01 ZN A 1 C1097 C1099 H1149 C104 C106 H156 H1057 D1081 G1137 S1139 H64 D88 G144 S146 3.6.4.13 0006508,0008233,0008236,0016020,0019062,0019087,0033644,0044423,0046718,0046872 C1KIK8 26682473 1201 GSVVIVGRINLAYAQQTRGEEGCQETSQTGRDKNQVEGEVQIVSTATQTFLATSINGVLWTVYHGAGTRTIASPKGPVTQMYTNVDKDLVGWQAPQGSRSLTPCTCGSSDLYLVTRHADVIPVRRRGDSRGSLLSPRPISYLKGSSGGPLLCPAGHAVGIFRTAVSTRGVAKAVDFIPVESLETTMR 5etx A 2.35 BS02 5RS A 1 Q1041 F1043 H1057 L1135 K1136 G1137 S1139 F1154 R1155 T1156 A1157 Q48 F50 H64 L142 K143 G144 S146 F161 R162 T163 A164 H1057 D1081 G1137 S1139 H64 D88 G144 S146 3.6.4.13 0006508,0008233,0008236,0016020,0019062,0019087,0033644,0044423,0046718,0046872 -logKd/Ki=6.81, Kd=154.3nM C1KIK8 26682473 1202 GSVVIVGRINLAYAQQTRGEEGCQETSQTGRDKNQVEGEVQIVSTATQTFLATSINGVLWTVYHGAGTRTIASPKGPVTQMYTNVDKDLVGWQAPQGSRSLTPCTCGSSDLYLVTRHADVIPVRRRGDSRGSLLSPRPISYLKGSSGGPLLCPAGHAVGIFRTAVSTRGVAKAVDFIPVESLETTMR 5etx A 2.35 BS03 5RS C 1 D1079 R1155 D86 R162 H1057 D1081 G1137 S1139 H64 D88 G144 S146 3.6.4.13 0006508,0008233,0008236,0016020,0019062,0019087,0033644,0044423,0046718,0046872 -logKd/Ki=6.81, Kd=154.3nM C1KIK8 26682473 1202 GSVVIVGRINLAYAQQTRGEEGCQETSQTGRDKNQVEGEVQIVSTATQTFLATSINGVLWTVYHGAGTRTIASPKGPVTQMYTNVDKDLVGWQAPQGSRSLTPCTCGSSDLYLVTRHADVIPVRRRGDSRGSLLSPRPISYLKGSSGGPLLCPAGHAVGIFRTAVSTRGVAKAVDFIPVESLETTMR 5etx B 2.35 BS01 ZN B 1 C1099 C1145 C112 C158 H1057 D1081 G1137 S1139 H70 D94 G150 S152 3.6.4.13 0006508,0008233,0008236,0016020,0019062,0019087,0033644,0044423,0046718,0046872 C1KIK8 26682473 1201 KKGSVVIVGRINLSGDTAYAQQTRGEEGCQETSQTGRDKNQVEGEVQIVSTATQTFLATSINGVLWTVYHGAGTRTIASPKGPVTQMYTNVDKDLVGWQAPQGSRSLTPCTCGSSDLYLVTRHADVIPVRRRGDSRGSLLSPRPISYLKGSSGGPLLCPAGHAVGIFRTAVSTRGVAKAVDFIPVESLETTMR 5etx B 2.35 BS02 5RS B 1 F1043 Y1056 H1057 V1078 D1081 I1132 L1135 K1136 G1137 S1139 F1154 R1155 T1156 A1157 F56 Y69 H70 V91 D94 I145 L148 K149 G150 S152 F167 R168 T169 A170 H1057 D1081 G1137 S1139 H70 D94 G150 S152 3.6.4.13 0006508,0008233,0008236,0016020,0019062,0019087,0033644,0044423,0046718,0046872 C1KIK8 26682473 1202 KKGSVVIVGRINLSGDTAYAQQTRGEEGCQETSQTGRDKNQVEGEVQIVSTATQTFLATSINGVLWTVYHGAGTRTIASPKGPVTQMYTNVDKDLVGWQAPQGSRSLTPCTCGSSDLYLVTRHADVIPVRRRGDSRGSLLSPRPISYLKGSSGGPLLCPAGHAVGIFRTAVSTRGVAKAVDFIPVESLETTMR 5etx C 2.35 BS01 ZN C 1 C1097 C1099 C1145 H1149 C111 C113 C159 H163 H1057 D1081 G1137 S1139 H71 D95 G151 S153 3.6.4.13 0006508,0008233,0008236,0016020,0019062,0019087,0033644,0044423,0046718,0046872 C1KIK8 26682473 1201 KKKGSVVIVGRINLSGDTAYAQQTRGEEGCQETSQTGRDKNQVEGEVQIVSTATQTFLATSINGVLWTVYHGAGTRTIASPKGPVTQMYTNVDKDLVGWQAPQGSRSLTPCTCGSSDLYLVTRHADVIPVRRRGDSRGSLLSPRPISYLKGSSGGPLLCPAGHAVGIFRTAVSTRGVAKAVDFIPVESLETTM 5etx C 2.35 BS02 5RS C 1 F1043 Y1056 H1057 V1078 D1081 I1132 L1135 K1136 G1137 S1139 F1154 R1155 T1156 A1157 V1158 F57 Y70 H71 V92 D95 I146 L149 K150 G151 S153 F168 R169 T170 A171 V172 H1057 D1081 G1137 S1139 H71 D95 G151 S153 3.6.4.13 0006508,0008233,0008236,0016020,0019062,0019087,0033644,0044423,0046718,0046872 C1KIK8 26682473 1202 KKKGSVVIVGRINLSGDTAYAQQTRGEEGCQETSQTGRDKNQVEGEVQIVSTATQTFLATSINGVLWTVYHGAGTRTIASPKGPVTQMYTNVDKDLVGWQAPQGSRSLTPCTCGSSDLYLVTRHADVIPVRRRGDSRGSLLSPRPISYLKGSSGGPLLCPAGHAVGIFRTAVSTRGVAKAVDFIPVESLETTM 5etx D 2.35 BS01 ZN D 1 C1097 C1099 C1145 C104 C106 C152 H1057 D1081 G1137 S1139 H64 D88 G144 S146 3.6.4.13 0006508,0008233,0008236,0016020,0019062,0019087,0033644,0044423,0046718,0046872 C1KIK8 26682473 1201 KGSVVIVGRINLYAQQTRGEEGCQETSQTGRDKNQVEGEVQIVSTATQTFLATSINGVLWTVYHGAGTRTIASPKGPVTQMYTNVDKDLVGWQAPQGSRSLTPCTCGSSDLYLVTRHADVIPVRRRGDSRGSLLSPRPISYLKGSSGGPLLCPAGHAVGIFRTAVSTRGVAKAVDFIPVESLETTMR 5etx D 2.35 BS02 5RS D 1 Q1041 F1043 H1057 L1135 K1136 G1137 S1139 F1154 R1155 T1156 A1157 Q48 F50 H64 L142 K143 G144 S146 F161 R162 T163 A164 H1057 D1081 G1137 S1139 H64 D88 G144 S146 3.6.4.13 0006508,0008233,0008236,0016020,0019062,0019087,0033644,0044423,0046718,0046872 C1KIK8 26682473 1202 KGSVVIVGRINLYAQQTRGEEGCQETSQTGRDKNQVEGEVQIVSTATQTFLATSINGVLWTVYHGAGTRTIASPKGPVTQMYTNVDKDLVGWQAPQGSRSLTPCTCGSSDLYLVTRHADVIPVRRRGDSRGSLLSPRPISYLKGSSGGPLLCPAGHAVGIFRTAVSTRGVAKAVDFIPVESLETTMR