5eie A 2.1 BS01 TZ2 A 1 W86 G121 Y124 E202 F297 Y337 W439 H447 Y449 W86 G121 Y124 E202 F292 Y332 W434 H442 Y444 G121 G122 G154 S203 A204 G242 F297 F299 E334 H447 G121 G122 G154 S203 A204 G242 F292 F294 E329 H442 3.1.1.7 0001919,0002076,0003990,0004104,0005515,0005518,0005576,0005604,0005615,0005794,0005886,0006581,0007155,0009986,0016020,0016787,0017171,0031594,0031623,0042166,0042802,0042803,0043236,0045202,0048471,0052689,0060041,0095500,0098552,0120162 Ki=23000pM -logKd/Ki=7.64, Ki=23nM P21836 26731630 605 EGREDPQLLVRVRGGQLRGIRLKAPGGPVSAFLGIPFAEPPVGSRRFMPPEPKRPWSGVLDATTFQNVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPASPTPVLIWIYGGGFYSGAASLDVYDGRFLAQVEGAVLVSMNYRVGTFGFLALPGSREAPGNVGLLDQRLALQWVQENIAAFGGDPMSVTLFGESAGAASVGMHILSLPSRSLFHRAVLQSGTPNGPWATVSAGEARRRATLLARLVGCPPNDTELIACLRTRPAQDLVDHEWHVLPQESIFRFSFVPVVDGDFLSDTPEALINTGDFQDLQVLVGVVKDEGSYFLVYGVPGFSKDNESLISRAQFLAGVRIGVPQASDLAAEAVVLHYTDWLHPEDPTHLRDAMSAVVGDHNVVCPVAQLAGRLAAQGARVYAYIFEHRASTLTWPLWMGVPHGYEIEFIFGLPLDPSLNYTTEERIFAQRLMKYWTNFARTGDPNDPRDSKSPQWPPYTTAAQQYVSLNLKPLEVRRGLRAQTCAFWNRFLPKLLSAT 5eie B 2.1 BS01 TZ2 B 1 W86 Y124 E202 F297 Y337 W439 H447 Y449 W84 Y122 E200 F290 Y330 W432 H440 Y442 G121 G122 G154 S203 A204 G242 F297 F299 E334 H447 G119 G120 G152 S201 A202 G240 F290 F292 E327 H440 3.1.1.7 0001919,0002076,0003990,0004104,0005515,0005518,0005576,0005604,0005615,0005794,0005886,0006581,0007155,0009986,0016020,0016787,0017171,0031594,0031623,0042166,0042802,0042803,0043236,0045202,0048471,0052689,0060041,0095500,0098552,0120162 Ki=23000pM P21836 26731630 604 REDPQLLVRVRGGQLRGIRLKAPGGPVSAFLGIPFAEPPVGSRRFMPPEPKRPWSGVLDATTFQNVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPASPTPVLIWIYGGGFYSGAASLDVYDGRFLAQVEGAVLVSMNYRVGTFGFLALPGSREAPGNVGLLDQRLALQWVQENIAAFGGDPMSVTLFGESAGAASVGMHILSLPSRSLFHRAVLQSGTPNGPWATVSAGEARRRATLLARLVGCPGNDTELIACLRTRPAQDLVDHEWHVLPQESIFRFSFVPVVDGDFLSDTPEALINTGDFQDLQVLVGVVKDEGSYFLVYGVPGFSKDNESLISRAQFLAGVRIGVPQASDLAAEAVVLHYTDWLHPEDPTHLRDAMSAVVGDHNVVCPVAQLAGRLAAQGARVYAYIFEHRASTLTWPLWMGVPHGYEIEFIFGLPLDPSLNYTTEERIFAQRLMKYWTNFARTGDPNDPRDSKSPQWPPYTTAAQQYVSLNLKPLEVRRGLRAQTCAFWNRFLPKLLSAT