5ehr A 1.7 BS01 5OD A 1 E110 R111 F113 T219 E249 E250 T253 L254 Q257 P491 K492 Q495 E96 R97 F99 T192 E216 E217 T220 L221 Q224 P451 K452 Q455 D425 C459 R465 T466 Q506 D385 C419 R425 T426 Q466 3.1.3.48 0004725,0006470,0016311 Kd=73nM -logKd/Ki=7.14, Kd=73nM IC50=70.0nM Q06124 27362227 601 RRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYDLYGGEKFATLAELVQYYMEHIELKYPLNCADPTSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESGDFVLSVRTGDSKVTHVMIRCQELKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETL 5ehr B 1.7 BS01 5OD B 1 E110 R111 F113 T219 E250 T253 L254 Q257 P491 K492 Q495 E95 R96 F98 T192 E214 T217 L218 Q221 P436 K437 Q440 D425 C459 R465 T466 Q506 D370 C404 R410 T411 Q451 3.1.3.48 0004725,0006470,0016311 Kd=73nM IC50=70.0nM Q06124 27362227 601 RRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYDLYGGEKFATLAELVQYYMEIELKYPLNCADPTSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESSHPGDFVLSVRTSKVTHVMIRCQELKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHVSDYINANIIMPKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETL