5ech A 2.14 BS01 JAA A 1 T121 F125 F220 V222 H328 D329 G331 W336 G537 T115 F119 F214 V216 H322 D323 G325 W330 G531 6.3.2.52 0005515,0005524,0005737,0009864,0010046,0010224,0016597,0016874,0016881,0018117,0019899,0045087,0070728,0071365,0080123,2000030 -logKd/Ki=3.80, Kd=0.16mM Q9SKE2 28223489 601 TFDMNRVIDEFDEMTRNAHQVQKQTLKEILLKNQSAIYLQNCGLNGNATDPEEAFKSMVPLVTDVELEPYIKRMVDGDTSPILTGHPVPAISLSSGTSQGRPKFIPFTDELMENTLQLFRTAFAFRNRDFPIDDNGKALQFIFSSKQYISTGGVPVGTATTNVYRNPNFKAGMKSITSPSCSPDEVIFSPDVHQALYCHLLSGILFRDQVQYVFAVFAHGLVHAFRTFEQVWEEIVTDIKDGVLSNRITVPSVRTAMSKLLTPNPELAETIRTKCMSLSNWYGLIPALFPNAKYVYGIMTGSMEPYVPKLRHYAGDLPLVSHDYGSSEGWIAANVTPRLSPEEATFAVIPNLGYFEFLPVSETGEGEEKPVGLTQVKIGEEYEVVITNYAGLYRYRLGDVVKVIGFYNNTPQLKFICRRNLILSINIDKNTERDLQLSVESAAKRLSEEKIEVIDFSSYIDVSTDPGHYAIFWEISGETNEDVLQDCCNCLDRAFIDAGYVSSRKCKTIGALELRVVAKGTFRKIQEHFLGLGSSAGQFKMPRCVKPSNAKVLQILCENVVSSYFSTAF 5ech A 2.14 BS02 ATP A 1 A96 I97 S98 F113 L117 M118 T121 G163 T164 A165 T166 N168 V169 G331 S332 S333 W336 K557 A90 I91 S92 F107 L111 M112 T115 G157 T158 A159 T160 N162 V163 G325 S326 S327 W330 K551 6.3.2.52 0005515,0005524,0005737,0009864,0010046,0010224,0016597,0016874,0016881,0018117,0019899,0045087,0070728,0071365,0080123,2000030 Q9SKE2 28223489 602 TFDMNRVIDEFDEMTRNAHQVQKQTLKEILLKNQSAIYLQNCGLNGNATDPEEAFKSMVPLVTDVELEPYIKRMVDGDTSPILTGHPVPAISLSSGTSQGRPKFIPFTDELMENTLQLFRTAFAFRNRDFPIDDNGKALQFIFSSKQYISTGGVPVGTATTNVYRNPNFKAGMKSITSPSCSPDEVIFSPDVHQALYCHLLSGILFRDQVQYVFAVFAHGLVHAFRTFEQVWEEIVTDIKDGVLSNRITVPSVRTAMSKLLTPNPELAETIRTKCMSLSNWYGLIPALFPNAKYVYGIMTGSMEPYVPKLRHYAGDLPLVSHDYGSSEGWIAANVTPRLSPEEATFAVIPNLGYFEFLPVSETGEGEEKPVGLTQVKIGEEYEVVITNYAGLYRYRLGDVVKVIGFYNNTPQLKFICRRNLILSINIDKNTERDLQLSVESAAKRLSEEKIEVIDFSSYIDVSTDPGHYAIFWEISGETNEDVLQDCCNCLDRAFIDAGYVSSRKCKTIGALELRVVAKGTFRKIQEHFLGLGSSAGQFKMPRCVKPSNAKVLQILCENVVSSYFSTAF 5ech B 2.14 BS01 GSH B 1 S13 F15 F37 K53 I54 E66 S10 F12 F34 K50 I51 E63 2.5.1.18 0004364,0005634,0005737,0005739,0005829,0006749,0009407,0009507,0009629,0009636,0016740,0019899,0043295,0048046,2000030 Q8L7C9 28223489 301 LPILLDYWPSMFGMRARVALREKGVEFEYREEDFSNKSPLLLQSNPIHKKIPVLVHNGKPVCESLNVVQYVDEAWPEKNPFFPSDPYGRAQARFWADFVDKKFTDAQFKVWGKKGEEQEAGKKEFIEAVKILESELGDKPYFGGDSFGYVDISLITFSSWFQAYEKFGNFSIESESPKLIAWAKRCMEKESVSKSLPDSEKIVAYAAEYRKNNL 5ech C 2.14 BS01 GSH C 1 Y10 F15 F37 K53 I54 S67 Y7 F12 F34 K50 I51 S64 2.5.1.18 0004364,0005634,0005737,0005739,0005829,0006749,0009407,0009507,0009629,0009636,0016740,0019899,0043295,0048046,2000030 Q8L7C9 28223489 301 LPILLDYWPSMFGMRARVALREKGVEFEYREEDFSNKSPLLLQSNPIHKKIPVLVHNGKPVCESLNVVQYVDEAWPEKNPFFPSDPYGRAQARFWADFVDKKFTDAQFKVWGKKGEEQEAGKKEFIEAVKILESELGDKPYFGGDSFGYVDISLITFSSWFQAYEKFGNFSIESESPKLIAWAKRCMEKESVSKSLPDSEKIVAYAAEYRKNNL 5ech D 2.14 BS01 JAA D 1 T121 L124 F125 F220 V222 H328 W336 T115 L118 F119 F214 V216 H322 W330 6.3.2.52 0005515,0005524,0005737,0009864,0010046,0010224,0016597,0016874,0016881,0018117,0019899,0045087,0070728,0071365,0080123,2000030 Q9SKE2 28223489 601 TFDMNRVIDEFDEMTRNAHQVQKQTLKEILLKNQSAIYLQNCGLNGNATDPEEAFKSMVPLVTDVELEPYIKRMVDGDTSPILTGHPVPAISLSSGTSQGRPKFIPFTDELMENTLQLFRTAFAFRNRDFPIDDNGKALQFIFSSKQYISTGGVPVGTATTNVYRNPNFKAGMKSITSPSCSPDEVIFSPDVHQALYCHLLSGILFRDQVQYVFAVFAHGLVHAFRTFEQVWEEIVTDIKDGVLSNRITVPSVRTAMSKLLTPNPELAETIRTKCMSLSNWYGLIPALFPNAKYVYGIMTGSMEPYVPKLRHYAGDLPLVSHDYGSSEGWIAANVTPRLSPEEATFAVIPNLGYFEFLPVSETGEGEEKPVGLTQVKIGEEYEVVITNYAGLYRYRLGDVVKVIGFYNNTPQLKFICRRNLILSINIDKNTERDLQLSVESAAKRLSEEKIEVIDFSSYIDVSTDPGHYAIFWEISGETNEDVLQDCCNCLDRAFIDAGYVSSRKCKTIGALELRVVAKGTFRKIQEHFLGLGSSAGQFKMPRCVKPSNAKVLQILCENVVSSYFSTAF 5ech D 2.14 BS02 ATP D 1 A96 I97 S98 P112 F113 L117 M118 T121 G163 T164 A165 N168 V169 G331 S332 S333 W336 K557 A90 I91 S92 P106 F107 L111 M112 T115 G157 T158 A159 N162 V163 G325 S326 S327 W330 K551 6.3.2.52 0005515,0005524,0005737,0009864,0010046,0010224,0016597,0016874,0016881,0018117,0019899,0045087,0070728,0071365,0080123,2000030 Q9SKE2 28223489 602 TFDMNRVIDEFDEMTRNAHQVQKQTLKEILLKNQSAIYLQNCGLNGNATDPEEAFKSMVPLVTDVELEPYIKRMVDGDTSPILTGHPVPAISLSSGTSQGRPKFIPFTDELMENTLQLFRTAFAFRNRDFPIDDNGKALQFIFSSKQYISTGGVPVGTATTNVYRNPNFKAGMKSITSPSCSPDEVIFSPDVHQALYCHLLSGILFRDQVQYVFAVFAHGLVHAFRTFEQVWEEIVTDIKDGVLSNRITVPSVRTAMSKLLTPNPELAETIRTKCMSLSNWYGLIPALFPNAKYVYGIMTGSMEPYVPKLRHYAGDLPLVSHDYGSSEGWIAANVTPRLSPEEATFAVIPNLGYFEFLPVSETGEGEEKPVGLTQVKIGEEYEVVITNYAGLYRYRLGDVVKVIGFYNNTPQLKFICRRNLILSINIDKNTERDLQLSVESAAKRLSEEKIEVIDFSSYIDVSTDPGHYAIFWEISGETNEDVLQDCCNCLDRAFIDAGYVSSRKCKTIGALELRVVAKGTFRKIQEHFLGLGSSAGQFKMPRCVKPSNAKVLQILCENVVSSYFSTAF 5ech E 2.14 BS01 GSH E 1 S13 F15 K53 E66 S67 S10 F12 K50 E63 S64 2.5.1.18 0004364,0005634,0005737,0005739,0005829,0006749,0009407,0009507,0009629,0009636,0016740,0019899,0043295,0048046,2000030 Q8L7C9 28223489 301 LPILLDYWPSMFGMRARVALREKGVEFEYREEDFSNKSPLLLQSNPIHKKIPVLVHNGKPVCESLNVVQYVDEAWPEKNPFFPSDPYGRAQARFWADFVDKKFTDAQFKVWGKKGEEQEAGKKEFIEAVKILESELGDKPYFGGDSFGYVDISLITFSSWFQAYEKFGNFSIESESPKLIAWAKRCMEKESVSKSLPDSEKIVAYAAEYRKNNL 5ech F 2.14 BS01 GSH F 1 F15 K53 S67 F12 K50 S64 2.5.1.18 0004364,0005634,0005737,0005739,0005829,0006749,0009407,0009507,0009629,0009636,0016740,0019899,0043295,0048046,2000030 Q8L7C9 28223489 301 LPILLDYWPSMFGMRARVALREKGVEFEYREEDFSNKSPLLLQSNPIHKKIPVLVHNGKPVCESLNVVQYVDEAWPEKNPFFPSDPYGRAQARFWADFVDKKFTDAQFKVWGKKGEEQEAGKKEFIEAVKILESELGDKPYFGGDSFGYVDISLITFSSWFQAYEKFGNFSIESESPKLIAWAKRCMEKESVSKSLPDSEKIVAYAAEYRKNNL