5ece A 2.2 BS01 5N2 A 1 H1184 G1185 F1188 F1197 H1201 I1212 Y1213 S1221 Y1224 H81 G82 F85 F94 H98 I104 Y105 S113 Y116 2.4.2.-,2.4.2.30 0003950 ic50=9nM -logKd/Ki=8.05, IC50=9nM IC50=9.0nM O95271 26546219 1402 AGTILLDLAPEDKEYQSVEEEMQSTIREHRDGGNAGGIFNRYNVIRIQKVVNKKLRERFCHRQKEVSEENHNHHNERMLFHGSPFINAIIHKGFDERHAYGAGIYFAENSSKSNQYVYGIGGGTGCPTHKDRSCYICHRQMLFCRVTLGKSFLQFSTIKMAHAPPGHHSVIGRPSVNGLAYAEYVIYRGEQAYPEYLITYQIMKPEAP 5ece A 2.2 BS02 ZN A 1 C1234 H1237 C1242 C1245 C126 H129 C134 C137 2.4.2.-,2.4.2.30 0003950 O95271 26546219 1403 AGTILLDLAPEDKEYQSVEEEMQSTIREHRDGGNAGGIFNRYNVIRIQKVVNKKLRERFCHRQKEVSEENHNHHNERMLFHGSPFINAIIHKGFDERHAYGAGIYFAENSSKSNQYVYGIGGGTGCPTHKDRSCYICHRQMLFCRVTLGKSFLQFSTIKMAHAPPGHHSVIGRPSVNGLAYAEYVIYRGEQAYPEYLITYQIMKPEAP 5ece B 2.2 BS01 5N2 B 1 H1184 G1185 F1188 F1197 D1198 H1201 I1212 Y1213 S1221 Y1224 E1291 H81 G82 F85 F94 D95 H98 I102 Y103 S111 Y114 E176 2.4.2.-,2.4.2.30 0003950 ic50=9nM IC50=9.0nM O95271 26546219 1403 AGTILLDLAPEDKEYQSVEEEMQSTIREHRDGGNAGGIFNRYNVIRIQKVVNKKLRERFCHRQKEVSEENHNHHNERMLFHGSPFINAIIHKGFDERHAAGIYFAENSSKSNQYVYGIGGGTGCPTHKDRSCYICHRQMLFCRVTLGKSFLQFSTIKMAHAPPGHHSVIGRPAYAEYVIYRGEQAYPEYLITYQIMKPE 5ece B 2.2 BS02 ZN B 1 C1234 H1237 C1242 C1245 C124 H127 C132 C135 2.4.2.-,2.4.2.30 0003950 O95271 26546219 1404 AGTILLDLAPEDKEYQSVEEEMQSTIREHRDGGNAGGIFNRYNVIRIQKVVNKKLRERFCHRQKEVSEENHNHHNERMLFHGSPFINAIIHKGFDERHAAGIYFAENSSKSNQYVYGIGGGTGCPTHKDRSCYICHRQMLFCRVTLGKSFLQFSTIKMAHAPPGHHSVIGRPAYAEYVIYRGEQAYPEYLITYQIMKPE 5ece C 2.2 BS01 5N2 C 1 H1184 G1185 F1188 I1192 F1197 H1201 I1212 Y1213 K1220 S1221 Y1224 E1291 H81 G82 F85 I89 F94 H98 I102 Y103 K110 S111 Y114 E179 2.4.2.-,2.4.2.30 0003950 ic50=9nM IC50=9.0nM O95271 26546219 1403 AGTILLDLAPEDKEYQSVEEEMQSTIREHRDGGNAGGIFNRYNVIRIQKVVNKKLRERFCHRQKEVSEENHNHHNERMLFHGSPFINAIIHKGFDERHAAGIYFAENSSKSNQYVYGIGGGTGCPTHKDRSCYICHRQMLFCRVTLGKSFLQFSTIKMAHAPPGHHSVIGRPSVLAYAEYVIYRGEQAYPEYLITYQIMKPEA 5ece C 2.2 BS02 ZN C 1 C1234 H1237 C1242 C1245 C124 H127 C132 C135 2.4.2.-,2.4.2.30 0003950 O95271 26546219 1404 AGTILLDLAPEDKEYQSVEEEMQSTIREHRDGGNAGGIFNRYNVIRIQKVVNKKLRERFCHRQKEVSEENHNHHNERMLFHGSPFINAIIHKGFDERHAAGIYFAENSSKSNQYVYGIGGGTGCPTHKDRSCYICHRQMLFCRVTLGKSFLQFSTIKMAHAPPGHHSVIGRPSVLAYAEYVIYRGEQAYPEYLITYQIMKPEA 5ece D 2.2 BS01 ZN D 1 C1234 H1237 C1242 C1245 C124 H127 C132 C135 2.4.2.-,2.4.2.30 0003950 O95271 26546219 1404 AGTILLDLAPEDKEYQSVEEEMQSTIREHRDGGNAGGIFNRYNVIRIQKVVNKKLRERFCHRQKEVSEENHNHHNERMLFHGSPFINAIIHKGFDERHAAGIYFAENSSKSNQYVYGIGGGTGCPTHKDRSCYICHRQMLFCRVTLGKSFLQFSTIKMAHAPPGHHSVIGRPLAYAEYVIYRGEQAYPEYLITYQIMKPEAP