5dh3 A 2.468 BS01 5BS A 1 L33 V41 E100 Y101 C102 G103 G105 D109 L153 L15 V23 E82 Y83 C84 G85 G87 D91 L135 D146 K148 G150 N151 D164 D173 T184 D128 K130 G132 N133 D146 D155 T166 2.7.11.1 0004672,0005524,0006468 ic50=38.1nM -logKd/Ki=7.42, IC50=38.1nM Q13188 27535619 401 LTKQPEEVFDVLEKLGEGSYGSVFKAIHKESGQVVAIKQVPVESDLQEIIKEISIMQQCDSPYVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLIEDEIATILKSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIGYNCVADIWSLGITSIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDDFTDFVKKCLVKNPEQRATATQLLQHPFIKNAKPVSILRDLITEAMEIKAKRHEEQQR 5dh3 B 2.468 BS01 5BS B 1 L33 V41 M99 E100 Y101 C102 G105 D109 L153 K298 L16 V24 M82 E83 Y84 C85 G88 D92 L136 K281 D146 K148 G150 N151 D164 D173 T184 D129 K131 G133 N134 D147 D156 T167 2.7.11.1 0004672,0005524,0006468 ic50=38.1nM Q13188 27535619 401 SLTKQPEEVFDVLEKLGEGSYGSVFKAIHKESGQVVAIKQVPVESDLQEIIKEISIMQQCDSPYVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLIEDEIATILKSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIGYNCVADIWSLGITSIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDDFTDFVKKCLVKNPEQRATATQLLQHPFIKNAKPVSILRDLITEAMEIKAKRH