5dfp A 2.2 BS01 59U A 1 A297 R299 E315 V342 M344 Y346 L347 G350 D354 L396 A49 R51 E67 V94 M96 Y98 L99 G102 D106 L148 D389 K391 D393 N394 D407 P416 T427 D141 K143 D145 N146 D159 P168 T179 2.7.11.1 0004672,0005524,0006468 Ki=22nM -logKd/Ki=7.66, Ki=22nM Ki=22nM, IC50=222nM Q13153 26713112 601 SDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIRQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQHQFLKIAKPLSSLTPLIAAAKEAT