5dey A 2.1 BS01 59T A 1 A297 K299 E315 V342 M344 Y346 L347 D393 L396 A48 K50 E66 V93 M95 Y97 L98 D144 L147 N389 K391 D393 N394 D407 P416 T427 N140 K142 D144 N145 D158 P167 T178 2.7.11.1 0004672,0005524,0006468 Ki=3.7nM -logKd/Ki=8.43, Ki=3.7nM Ki=3.7nM, IC50=69nM Q13153 26713112 601 DEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRNIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSEMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQHQFLKIAKPLSSLTPLIAAAKEATKNN 5dey B 2.1 BS01 59T B 1 A297 K299 M319 M344 Y346 L347 D393 L396 T406 A43 K45 M65 M90 Y92 L93 D139 L142 T152 N389 K391 D393 N394 D407 T427 N135 K137 D139 N140 D153 T166 2.7.11.1 0004672,0005524,0006468 Ki=3.7nM Ki=3.7nM, IC50=69nM Q13153 26713112 601 EKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRNIKSDNILLGMDGSVKLTDFGFQSKRSEMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQHQFLKIAKPLSSLTPLIAAAKEATK