5d7q A 2.01 BS01 ZN A 1 C195 C200 C221 C224 C142 C147 C168 C171 P94 D95 F96 R97 N168 D170 H187 P41 D42 F43 R44 N115 D117 H134 2.3.1.-,2.3.1.286 0017136,0051287,0070403 Q8IXJ6 26625292 401 HMERLLDELTLEGVARYMQSERCRRVICLVGAGISTSAGIPDFRSPSTGLYDNLEKYHLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFMRLLKDKGLLLRCYTQNIDTLERIAGLEQEDLVEAHGTFYTSHCVSASCRHEYPLSWMKEKIFSEVTPKCEDCQSLVKPDIVFFGESLPARFFSCMQSDFLKVDLLLVMGTSLQVQPFASLISKAPLSTPRLLINKEKAGQSDPFLGMIMGLGGGMDFDSKKAYRDVAWLGECDQGCLALAELLGWKKELEDLVRREHASIDA 5d7q A 2.01 BS02 AR6 A 1 G84 A85 G86 T89 D95 F96 R97 Q167 H187 F235 G261 T262 S263 V266 N286 K287 E288 E323 C324 G31 A32 G33 T36 D42 F43 R44 Q114 H134 F182 G208 T209 S210 V213 N233 K234 E235 E270 C271 P94 D95 F96 R97 N168 D170 H187 P41 D42 F43 R44 N115 D117 H134 2.3.1.-,2.3.1.286 0017136,0051287,0070403 Q8IXJ6 26625292 402 HMERLLDELTLEGVARYMQSERCRRVICLVGAGISTSAGIPDFRSPSTGLYDNLEKYHLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFMRLLKDKGLLLRCYTQNIDTLERIAGLEQEDLVEAHGTFYTSHCVSASCRHEYPLSWMKEKIFSEVTPKCEDCQSLVKPDIVFFGESLPARFFSCMQSDFLKVDLLLVMGTSLQVQPFASLISKAPLSTPRLLINKEKAGQSDPFLGMIMGLGGGMDFDSKKAYRDVAWLGECDQGCLALAELLGWKKELEDLVRREHASIDA 5d7q A 2.01 BS03 4I5 A 1 P94 F96 Q167 N168 I169 D170 I232 F234 P41 F43 Q114 N115 I116 D117 I179 F181 P94 D95 F96 R97 N168 D170 H187 P41 D42 F43 R44 N115 D117 H134 2.3.1.-,2.3.1.286 0017136,0051287,0070403 ic50=2.8uM IC50=2770nM Q8IXJ6 26625292 403 HMERLLDELTLEGVARYMQSERCRRVICLVGAGISTSAGIPDFRSPSTGLYDNLEKYHLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFMRLLKDKGLLLRCYTQNIDTLERIAGLEQEDLVEAHGTFYTSHCVSASCRHEYPLSWMKEKIFSEVTPKCEDCQSLVKPDIVFFGESLPARFFSCMQSDFLKVDLLLVMGTSLQVQPFASLISKAPLSTPRLLINKEKAGQSDPFLGMIMGLGGGMDFDSKKAYRDVAWLGECDQGCLALAELLGWKKELEDLVRREHASIDA 5d7q A 2.01 BS04 4I5 A 2 I93 F119 L138 Y139 G141 D170 I40 F66 L85 Y86 G88 D117 P94 D95 F96 R97 N168 D170 H187 P41 D42 F43 R44 N115 D117 H134 2.3.1.-,2.3.1.286 0017136,0051287,0070403 ic50=2.8uM IC50=2770nM Q8IXJ6 26625292 404 HMERLLDELTLEGVARYMQSERCRRVICLVGAGISTSAGIPDFRSPSTGLYDNLEKYHLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFMRLLKDKGLLLRCYTQNIDTLERIAGLEQEDLVEAHGTFYTSHCVSASCRHEYPLSWMKEKIFSEVTPKCEDCQSLVKPDIVFFGESLPARFFSCMQSDFLKVDLLLVMGTSLQVQPFASLISKAPLSTPRLLINKEKAGQSDPFLGMIMGLGGGMDFDSKKAYRDVAWLGECDQGCLALAELLGWKKELEDLVRREHASIDA 5d7q B 2.01 BS01 ZN B 1 C195 C200 C221 C224 C140 C145 C166 C169 P94 D95 F96 R97 N168 D170 H187 P39 D40 F41 R42 N113 D115 H132 2.3.1.-,2.3.1.286 0017136,0051287,0070403 Q8IXJ6 26625292 401 ERLLDELTLEGVARYMQSERCRRVICLVGAGISTSAGIPDFRSPSTGLYDNLEKYHLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFMRLLKDKGLLLRCYTQNIDTLERIAGLEQEDLVEAHGTFYTSHCVSASCRHEYPLSWMKEKIFSEVTPKCEDCQSLVKPDIVFFGESLPARFFSCMQSDFLKVDLLLVMGTSLQVQPFASLISKAPLSTPRLLINKEKAGQSDPFLGMIMGLGGGMDFDSKKAYRDVAWLGECDQGCLALAELLGWKKELEDLVRREHASIDAQ 5d7q B 2.01 BS02 AR6 B 1 G84 A85 G86 T89 D95 F96 R97 Y104 Q167 H187 F235 G261 T262 S263 V266 N286 K287 E288 E323 C324 G29 A30 G31 T34 D40 F41 R42 Y49 Q112 H132 F180 G206 T207 S208 V211 N231 K232 E233 E268 C269 P94 D95 F96 R97 N168 D170 H187 P39 D40 F41 R42 N113 D115 H132 2.3.1.-,2.3.1.286 0017136,0051287,0070403 Q8IXJ6 26625292 402 ERLLDELTLEGVARYMQSERCRRVICLVGAGISTSAGIPDFRSPSTGLYDNLEKYHLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFMRLLKDKGLLLRCYTQNIDTLERIAGLEQEDLVEAHGTFYTSHCVSASCRHEYPLSWMKEKIFSEVTPKCEDCQSLVKPDIVFFGESLPARFFSCMQSDFLKVDLLLVMGTSLQVQPFASLISKAPLSTPRLLINKEKAGQSDPFLGMIMGLGGGMDFDSKKAYRDVAWLGECDQGCLALAELLGWKKELEDLVRREHASIDAQ 5d7q B 2.01 BS03 4I5 B 1 P94 F96 Q167 N168 I169 D170 I232 F234 P39 F41 Q112 N113 I114 D115 I177 F179 P94 D95 F96 R97 N168 D170 H187 P39 D40 F41 R42 N113 D115 H132 2.3.1.-,2.3.1.286 0017136,0051287,0070403 ic50=2.8uM IC50=2770nM Q8IXJ6 26625292 403 ERLLDELTLEGVARYMQSERCRRVICLVGAGISTSAGIPDFRSPSTGLYDNLEKYHLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFMRLLKDKGLLLRCYTQNIDTLERIAGLEQEDLVEAHGTFYTSHCVSASCRHEYPLSWMKEKIFSEVTPKCEDCQSLVKPDIVFFGESLPARFFSCMQSDFLKVDLLLVMGTSLQVQPFASLISKAPLSTPRLLINKEKAGQSDPFLGMIMGLGGGMDFDSKKAYRDVAWLGECDQGCLALAELLGWKKELEDLVRREHASIDAQ 5d7q B 2.01 BS04 4I5 B 2 I93 A135 L138 Y139 G141 D170 F190 I38 A80 L83 Y84 G86 D115 F135 P94 D95 F96 R97 N168 D170 H187 P39 D40 F41 R42 N113 D115 H132 2.3.1.-,2.3.1.286 0017136,0051287,0070403 ic50=2.8uM IC50=2770nM Q8IXJ6 26625292 404 ERLLDELTLEGVARYMQSERCRRVICLVGAGISTSAGIPDFRSPSTGLYDNLEKYHLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFMRLLKDKGLLLRCYTQNIDTLERIAGLEQEDLVEAHGTFYTSHCVSASCRHEYPLSWMKEKIFSEVTPKCEDCQSLVKPDIVFFGESLPARFFSCMQSDFLKVDLLLVMGTSLQVQPFASLISKAPLSTPRLLINKEKAGQSDPFLGMIMGLGGGMDFDSKKAYRDVAWLGECDQGCLALAELLGWKKELEDLVRREHASIDAQ