5cpr B 2.22 BS01 ZN B 1 C275 C319 C321 C324 C173 C217 C219 C222 2.1.1.361,2.1.1.362 0042799 Q4FZB7 28114273 401 MSAKELCENDDLATSLVLDPYLGFQTHKMNRQEELKEVIERFKKDEHLEKAFKCLTSGEWARHYFLNKNKMQEKLFKEHVFIYLRMFATDSGFEILPCNRYSSEQNGAKIVATKEWKRNDKIELLVGCIAELSEIEENMLLRHGENDFSVMYSTRKNCAQLWLGPAAFINHDCRPNCKFVSTGRDTACVKALRDIEPGEEISCYYGDGFFGENNEFCECYTCERRGTGAFKS 5cpr B 2.22 BS02 SAM B 1 H98 Y203 S205 E206 G209 A210 F250 A269 F270 N272 H273 Y307 F312 C321 H27 Y101 S103 E104 G107 A108 F148 A167 F168 N170 H171 Y205 F210 C219 2.1.1.361,2.1.1.362 0042799 Q4FZB7 28114273 402 MSAKELCENDDLATSLVLDPYLGFQTHKMNRQEELKEVIERFKKDEHLEKAFKCLTSGEWARHYFLNKNKMQEKLFKEHVFIYLRMFATDSGFEILPCNRYSSEQNGAKIVATKEWKRNDKIELLVGCIAELSEIEENMLLRHGENDFSVMYSTRKNCAQLWLGPAAFINHDCRPNCKFVSTGRDTACVKALRDIEPGEEISCYYGDGFFGENNEFCECYTCERRGTGAFKS 5cpr B 2.22 BS03 539 B 1 G229 S251 V252 W264 A268 A269 F281 A289 Y307 G127 S149 V150 W162 A166 A167 F179 A187 Y205 2.1.1.361,2.1.1.362 0042799 Kd=27.8nM -logKd/Ki=7.56, Kd=27.5nM IC50=25nM Q4FZB7 28114273 403 MSAKELCENDDLATSLVLDPYLGFQTHKMNRQEELKEVIERFKKDEHLEKAFKCLTSGEWARHYFLNKNKMQEKLFKEHVFIYLRMFATDSGFEILPCNRYSSEQNGAKIVATKEWKRNDKIELLVGCIAELSEIEENMLLRHGENDFSVMYSTRKNCAQLWLGPAAFINHDCRPNCKFVSTGRDTACVKALRDIEPGEEISCYYGDGFFGENNEFCECYTCERRGTGAFKS