5clp A 1.684 BS01 42J A 1 V66 K68 F113 M163 I174 D175 V64 K66 F111 M156 I167 D168 D156 K158 N161 D175 P184 S194 D149 K151 N154 D168 P177 S187 2.7.11.1 0004672,0004674,0005524,0006468 IC50=700000nM P68400 28451126 401 GPVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVK 5clp A 1.684 BS02 42J A 2 L45 G46 V53 H160 N161 D175 L43 G44 V51 H153 N154 D168 D156 K158 N161 D175 P184 S194 D149 K151 N154 D168 P177 S187 2.7.11.1 0004672,0004674,0005524,0006468 IC50=700000nM P68400 28451126 402 GPVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVK 5clp A 1.684 BS03 42J A 3 Q36 Y39 L41 I69 D103 Q34 Y37 L39 I67 D101 D156 K158 N161 D175 P184 S194 D149 K151 N154 D168 P177 S187 2.7.11.1 0004672,0004674,0005524,0006468 IC50=700000nM P68400 28451126 403 GPVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVK 5clp A 1.684 BS04 42J A 4 L128 P159 V162 I164 M221 M225 L121 P152 V155 I157 M214 M218 D156 K158 N161 D175 P184 S194 D149 K151 N154 D168 P177 S187 2.7.11.1 0004672,0004674,0005524,0006468 IC50=700000nM P68400 28451126 404 GPVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVK 5clp A 1.684 BS05 42J A 5 E282 V285 Q290 V293 E275 V278 Q283 V286 D156 K158 N161 D175 P184 S194 D149 K151 N154 D168 P177 S187 2.7.11.1 0004672,0004674,0005524,0006468 IC50=700000nM P68400 28451126 405 GPVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVK 5clp A 1.684 BS06 42J A 6 E282 R283 V285 H286 E275 R276 V278 H279 D156 K158 N161 D175 P184 S194 D149 K151 N154 D168 P177 S187 2.7.11.1 0004672,0004674,0005524,0006468 IC50=700000nM P68400 28451126 406 GPVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVK 5clp B 1.684 BS01 42J B 1 V66 K68 M163 I174 D175 V64 K66 M161 I172 D173 D156 K158 N161 D175 P184 S194 D154 K156 N159 D173 P182 S192 2.7.11.1 0004672,0004674,0005524,0006468 IC50=700000nM P68400 28451126 401 GPVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVK 5clp B 1.684 BS02 42J B 2 H160 N161 M163 D175 H158 N159 M161 D173 D156 K158 N161 D175 P184 S194 D154 K156 N159 D173 P182 S192 2.7.11.1 0004672,0004674,0005524,0006468 IC50=700000nM P68400 28451126 402 GPVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVK 5clp B 1.684 BS03 42J B 3 L128 P159 V162 I164 M221 M225 L126 P157 V160 I162 M219 M223 D156 K158 N161 D175 P184 S194 D154 K156 N159 D173 P182 S192 2.7.11.1 0004672,0004674,0005524,0006468 IC50=700000nM P68400 28451126 403 GPVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVK 5clp B 1.684 BS04 42J B 4 Q36 D37 Y39 L41 V67 I69 Q34 D35 Y37 L39 V65 I67 D156 K158 N161 D175 P184 S194 D154 K156 N159 D173 P182 S192 2.7.11.1 0004672,0004674,0005524,0006468 IC50=700000nM P68400 28451126 404 GPVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVK 5clp B 1.684 BS05 42J B 5 N16 T17 W24 H183 Q186 N14 T15 W22 H181 Q184 D156 K158 N161 D175 P184 S194 D154 K156 N159 D173 P182 S192 2.7.11.1 0004672,0004674,0005524,0006468 IC50=700000nM P68400 28451126 405 GPVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVK