5c5h A 2.401 BS01 MG A 1 R9 C34 D38 Q74 R11 C36 D40 Q76 T142 S162 H186 G270 E273 F356 G361 T144 S163 H187 G271 E274 F357 G362 6.2.1.26 0005524,0008756,0009234,0016874,0016877,0032991,0042802 P37353 26394156 501 SHMIFSDWPWRHWRQVRGETIALRLNDEQLNWRELCARVDELASGFAVQGVVEGSGVMLRAWNTPQTLLAWLALLQCGARVLPVNPQLPQPLLEELLPNLTLQFALVPDGENTFPALTSLHIQLVEGAHAATWQPTRLCSMTLTSSTGLPKAAVHTYQAHLASAQGVLSLIPFGDHDDWLLSLPLFHVSGQGIMWKWLYAGARMTVRDKQPLEQMLAGCTHASLVPTQLWRLLVNRSSVSLKAVLLGGAAIPVELTEQAREQGIRCFCGYGLTEFASTVCAKEADGLADVGSPLPGREVKIVNNEVWLRAASMAEGYWRNGQLVSLVNDEGWYATRDRGEMHNGKLTIVGRLDNLFFSGGEGIQPEEVERVIAAHPAVLQVFIVPVADKFGHRPVAVMEYDHESVDLSEWVKDKLARFQQPVRWLTLPPKISRQALKEWVQRQ 5c5h A 2.401 BS02 4YB A 1 S188 L223 L244 G246 G247 A248 A249 Y269 G270 L271 T272 S276 T277 D336 I347 K437 S189 L224 L245 G247 G248 A249 A250 Y270 G271 L272 T273 S277 T278 D337 I348 K430 T142 S162 H186 G270 E273 F356 G361 T144 S163 H187 G271 E274 F357 G362 6.2.1.26 0005524,0008756,0009234,0016874,0016877,0032991,0042802 Kd=394nM -logKd/Ki=6.40, Kd=394nM P37353 26394156 502 SHMIFSDWPWRHWRQVRGETIALRLNDEQLNWRELCARVDELASGFAVQGVVEGSGVMLRAWNTPQTLLAWLALLQCGARVLPVNPQLPQPLLEELLPNLTLQFALVPDGENTFPALTSLHIQLVEGAHAATWQPTRLCSMTLTSSTGLPKAAVHTYQAHLASAQGVLSLIPFGDHDDWLLSLPLFHVSGQGIMWKWLYAGARMTVRDKQPLEQMLAGCTHASLVPTQLWRLLVNRSSVSLKAVLLGGAAIPVELTEQAREQGIRCFCGYGLTEFASTVCAKEADGLADVGSPLPGREVKIVNNEVWLRAASMAEGYWRNGQLVSLVNDEGWYATRDRGEMHNGKLTIVGRLDNLFFSGGEGIQPEEVERVIAAHPAVLQVFIVPVADKFGHRPVAVMEYDHESVDLSEWVKDKLARFQQPVRWLTLPPKISRQALKEWVQRQ 5c5h A 2.401 BS03 MG B 1 Q132 P133 T134 Q134 P135 T136 T142 S162 H186 G270 E273 F356 G361 T144 S163 H187 G271 E274 F357 G362 6.2.1.26 0005524,0008756,0009234,0016874,0016877,0032991,0042802 P37353 26394156 501 SHMIFSDWPWRHWRQVRGETIALRLNDEQLNWRELCARVDELASGFAVQGVVEGSGVMLRAWNTPQTLLAWLALLQCGARVLPVNPQLPQPLLEELLPNLTLQFALVPDGENTFPALTSLHIQLVEGAHAATWQPTRLCSMTLTSSTGLPKAAVHTYQAHLASAQGVLSLIPFGDHDDWLLSLPLFHVSGQGIMWKWLYAGARMTVRDKQPLEQMLAGCTHASLVPTQLWRLLVNRSSVSLKAVLLGGAAIPVELTEQAREQGIRCFCGYGLTEFASTVCAKEADGLADVGSPLPGREVKIVNNEVWLRAASMAEGYWRNGQLVSLVNDEGWYATRDRGEMHNGKLTIVGRLDNLFFSGGEGIQPEEVERVIAAHPAVLQVFIVPVADKFGHRPVAVMEYDHESVDLSEWVKDKLARFQQPVRWLTLPPKISRQALKEWVQRQ 5c5h B 2.401 BS01 MG B 2 N61 P183 N62 P182 T142 S162 H186 G270 E273 F356 G361 T143 S161 H185 G269 E272 F355 G360 6.2.1.26 0005524,0008756,0009234,0016874,0016877,0032991,0042802 P37353 26394156 502 HMIFSDWPWRHWRQVRGETIALRLNDEQLNWRELCARVDELASGFAVQGVVEGSGVMLRAWNTPQTLLAWLALLQCGARVLPVNPQLPQPLLEELLPNLTLQFALVPDGENTFPALTSLHIQLVEGAHAATWQPTRLCSMTLTSGGLPKAAVHTYQAHLASAQGVLSLIPFGDHDDWLLSLPLFHVSGQGIMWKWLYAGARMTVRDKQPLEQMLAGCTHASLVPTQLWRLLVNRSSVSLKAVLLGGAAIPVELTEQAREQGIRCFCGYGLTEFASTVCAKEADGLADVGSPLPGREVKIVNNEVWLRAASMAEGYWRNGQLVSLVNDEGWYATRDRGEMHNGKLTIVGRLDNLFFSGGEGIQPEEVERVIAAHPAVLQVFIVPVADKEFGHRPVAVMEYDHESVDLSEWVKDKLARFQQPVRWLTLPPELKGIKISRQALKEWVQRQQ 5c5h B 2.401 BS02 4YB B 1 H186 S188 L244 G246 G247 A248 A249 G270 L271 T272 T277 D336 K437 H185 S187 L243 G245 G246 A247 A248 G269 L270 T271 T276 D335 K434 T142 S162 H186 G270 E273 F356 G361 T143 S161 H185 G269 E272 F355 G360 6.2.1.26 0005524,0008756,0009234,0016874,0016877,0032991,0042802 Kd=394nM P37353 26394156 503 HMIFSDWPWRHWRQVRGETIALRLNDEQLNWRELCARVDELASGFAVQGVVEGSGVMLRAWNTPQTLLAWLALLQCGARVLPVNPQLPQPLLEELLPNLTLQFALVPDGENTFPALTSLHIQLVEGAHAATWQPTRLCSMTLTSGGLPKAAVHTYQAHLASAQGVLSLIPFGDHDDWLLSLPLFHVSGQGIMWKWLYAGARMTVRDKQPLEQMLAGCTHASLVPTQLWRLLVNRSSVSLKAVLLGGAAIPVELTEQAREQGIRCFCGYGLTEFASTVCAKEADGLADVGSPLPGREVKIVNNEVWLRAASMAEGYWRNGQLVSLVNDEGWYATRDRGEMHNGKLTIVGRLDNLFFSGGEGIQPEEVERVIAAHPAVLQVFIVPVADKEFGHRPVAVMEYDHESVDLSEWVKDKLARFQQPVRWLTLPPELKGIKISRQALKEWVQRQQ