5bpc A 2.0 BS01 dna D 0 K35 A38 Y39 P63 G64 V65 G66 K68 I69 K26 A29 Y30 P54 G55 V56 G57 K59 I60 D190 D192 D256 D181 D183 D240 2.7.7.7,4.2.99.-,4.2.99.18 0001701,0003677,0003684,0003887,0003906,0005515,0005634,0005654,0005737,0005874,0005876,0006259,0006260,0006261,0006281,0006284,0006287,0006290,0006297,0006303,0006915,0006954,0006974,0007435,0008017,0008630,0010332,0016445,0016446,0016779,0016829,0019899,0032991,0034061,0045471,0046872,0048535,0048536,0048872,0051402,0051575,0055093,0071707,0071897,0140078 P06746 26243878 1 ~ 5 TLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPAGEPLPVDSEKDIFDYIQWKYREPKDRSE 5bpc A 2.0 BS02 dna P 0 S104 G105 G107 P108 S109 A110 S95 G96 G98 P99 S100 A101 D190 D192 D256 D181 D183 D240 2.7.7.7,4.2.99.-,4.2.99.18 0001701,0003677,0003684,0003887,0003906,0005515,0005634,0005654,0005737,0005874,0005876,0006259,0006260,0006261,0006281,0006284,0006287,0006290,0006297,0006303,0006915,0006954,0006974,0007435,0008017,0008630,0010332,0016445,0016446,0016779,0016829,0019899,0032991,0034061,0045471,0046872,0048535,0048536,0048872,0051402,0051575,0055093,0071707,0071897,0140078 P06746 26243878 1 ~ 10 TLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPAGEPLPVDSEKDIFDYIQWKYREPKDRSE 5bpc A 2.0 BS03 dna T 0 H34 S229 K230 G231 T233 R283 H25 S216 K217 G218 T220 R267 D190 D192 D256 D181 D183 D240 2.7.7.7,4.2.99.-,4.2.99.18 0001701,0003677,0003684,0003887,0003906,0005515,0005634,0005654,0005737,0005874,0005876,0006259,0006260,0006261,0006281,0006284,0006287,0006290,0006297,0006303,0006915,0006954,0006974,0007435,0008017,0008630,0010332,0016445,0016446,0016779,0016829,0019899,0032991,0034061,0045471,0046872,0048535,0048536,0048872,0051402,0051575,0055093,0071707,0071897,0140078 P06746 26243878 1 ~ 16 TLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPAGEPLPVDSEKDIFDYIQWKYREPKDRSE 5bpc A 2.0 BS04 MN A 1 D190 D192 D256 D181 D183 D240 D190 D192 D256 D181 D183 D240 2.7.7.7,4.2.99.-,4.2.99.18 0001701,0003677,0003684,0003887,0003906,0005515,0005634,0005654,0005737,0005874,0005876,0006259,0006260,0006261,0006281,0006284,0006287,0006290,0006297,0006303,0006915,0006954,0006974,0007435,0008017,0008630,0010332,0016445,0016446,0016779,0016829,0019899,0032991,0034061,0045471,0046872,0048535,0048536,0048872,0051402,0051575,0055093,0071707,0071897,0140078 P06746 26243878 401 TLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPAGEPLPVDSEKDIFDYIQWKYREPKDRSE 5bpc A 2.0 BS05 MN A 2 D190 D192 D181 D183 D190 D192 D256 D181 D183 D240 2.7.7.7,4.2.99.-,4.2.99.18 0001701,0003677,0003684,0003887,0003906,0005515,0005634,0005654,0005737,0005874,0005876,0006259,0006260,0006261,0006281,0006284,0006287,0006290,0006297,0006303,0006915,0006954,0006974,0007435,0008017,0008630,0010332,0016445,0016446,0016779,0016829,0019899,0032991,0034061,0045471,0046872,0048535,0048536,0048872,0051402,0051575,0055093,0071707,0071897,0140078 P06746 26243878 402 TLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPAGEPLPVDSEKDIFDYIQWKYREPKDRSE 5bpc A 2.0 BS06 F2A A 1 G179 S180 R183 S188 G189 D190 D192 Y271 T273 G274 D276 N279 G170 S171 R174 S179 G180 D181 D183 Y255 T257 G258 D260 N263 D190 D192 D256 D181 D183 D240 2.7.7.7,4.2.99.-,4.2.99.18 0001701,0003677,0003684,0003887,0003906,0005515,0005634,0005654,0005737,0005874,0005876,0006259,0006260,0006261,0006281,0006284,0006287,0006290,0006297,0006303,0006915,0006954,0006974,0007435,0008017,0008630,0010332,0016445,0016446,0016779,0016829,0019899,0032991,0034061,0045471,0046872,0048535,0048536,0048872,0051402,0051575,0055093,0071707,0071897,0140078 Ki=5000nM P06746 26243878 405 TLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPAGEPLPVDSEKDIFDYIQWKYREPKDRSE