5axb A 1.65 BS01 NAD A 1 T157 T158 T159 N191 G222 D223 V224 T242 E243 I244 N248 T275 T276 I281 I299 G300 N346 H353 T154 T155 T156 N188 G219 D220 V221 T239 E240 I241 N245 T272 T273 I278 I296 G297 N343 H350 H55 S78 S83 D131 E156 N181 K186 D190 N191 C195 H301 H353 S361 Q365 H52 S75 S80 D128 E153 N178 K183 D187 N188 C192 H298 H350 S358 Q362 3.13.2.1 0004013,0005507,0005515,0005634,0005737,0005783,0005829,0006730,0016787,0019510,0042470,0042802,0051287 P50247 501 KLPYKVADIGLAAWGRKALDIAENEMPGLMRMREMYSASKPLKGARIAGCLHMTVETAVLIETLVALGAEVRWSSCNIFSTQDHAAAAIAKAGIPVFAWKGETDEEYLWCIEQTLHFKDGPLNMILDDGGDLTNLIHTKYPQLLSGIRGISEETTTGVHNLYKMMSNGILKVPAINVNDSVTKSKFDNLYGCRESLIDGIKRATDVMIAGKVAVVAGYGDVGKGCAQALRGFGARVIITEIDPINALQAAMEGYEVTTMDEACKEGNIFVTTTGCVDIILGRHFEQMKDDAIVCNIGHFDVEIDVKWLNENAVEKVNIKPQVDRYWLKNGRRIILLAEGRLVNLGCAMGHPSFVMSNSFTNQVMAQIELWTHPDKYPVGVHFLPKKLDEAVAEAHLGKLNVKLTKLTEKQAQYLGMPINGPFKPDHYRY 5axb A 1.65 BS02 NRN A 1 H55 T57 E59 E156 T157 K186 D190 L347 H353 M358 H52 T54 E56 E153 T154 K183 D187 L344 H350 M355 H55 S78 S83 D131 E156 N181 K186 D190 N191 C195 H301 H353 S361 Q365 H52 S75 S80 D128 E153 N178 K183 D187 N188 C192 H298 H350 S358 Q362 3.13.2.1 0004013,0005507,0005515,0005634,0005737,0005783,0005829,0006730,0016787,0019510,0042470,0042802,0051287 Ki=11.1nM P50247 502 KLPYKVADIGLAAWGRKALDIAENEMPGLMRMREMYSASKPLKGARIAGCLHMTVETAVLIETLVALGAEVRWSSCNIFSTQDHAAAAIAKAGIPVFAWKGETDEEYLWCIEQTLHFKDGPLNMILDDGGDLTNLIHTKYPQLLSGIRGISEETTTGVHNLYKMMSNGILKVPAINVNDSVTKSKFDNLYGCRESLIDGIKRATDVMIAGKVAVVAGYGDVGKGCAQALRGFGARVIITEIDPINALQAAMEGYEVTTMDEACKEGNIFVTTTGCVDIILGRHFEQMKDDAIVCNIGHFDVEIDVKWLNENAVEKVNIKPQVDRYWLKNGRRIILLAEGRLVNLGCAMGHPSFVMSNSFTNQVMAQIELWTHPDKYPVGVHFLPKKLDEAVAEAHLGKLNVKLTKLTEKQAQYLGMPINGPFKPDHYRY 5axb C 1.65 BS01 NAD C 1 T157 T158 T159 N191 G222 D223 V224 T242 E243 I244 N248 T275 T276 I281 I299 G300 H301 N346 H353 T155 T156 T157 N189 G220 D221 V222 T240 E241 I242 N246 T273 T274 I279 I297 G298 H299 N344 H351 3.13.2.1 0004013,0005507,0005515,0005634,0005737,0005783,0005829,0006730,0016787,0019510,0042470,0042802,0051287 P50247 501 DKLPYKVADIGLAAWGRKALDIAENEMPGLMRMREMYSASKPLKGARIAGCLHMTVETAVLIETLVALGAEVRWSSCNIFSTQDHAAAAIAKAGIPVFAWKGETDEEYLWCIEQTLHFKDGPLNMILDDGGDLTNLIHTKYPQLLSGIRGISEETTTGVHNLYKMMSNGILKVPAINVNDSVTKSKFDNLYGCRESLIDGIKRATDVMIAGKVAVVAGYGDVGKGCAQALRGFGARVIITEIDPINALQAAMEGYEVTTMDEACKEGNIFVTTTGCVDIILGRHFEQMKDDAIVCNIGHFDVEIDVKWLNENAVEKVNIKPQVDRYWLKNGRRIILLAEGRLVNLGCAMGHPSFVMSNSFTNQVMAQIELWTHPDKYPVGVHFLPKKLDEAVAEAHLGKLNVKLTKLTEKQAQYLGMPINGPFKPDHYRY 5axb C 1.65 BS02 NRN C 1 H55 T57 E156 T157 K186 D190 L347 H353 M358 H53 T55 E154 T155 K184 D188 L345 H351 M356 3.13.2.1 0004013,0005507,0005515,0005634,0005737,0005783,0005829,0006730,0016787,0019510,0042470,0042802,0051287 Ki=11.1nM P50247 502 DKLPYKVADIGLAAWGRKALDIAENEMPGLMRMREMYSASKPLKGARIAGCLHMTVETAVLIETLVALGAEVRWSSCNIFSTQDHAAAAIAKAGIPVFAWKGETDEEYLWCIEQTLHFKDGPLNMILDDGGDLTNLIHTKYPQLLSGIRGISEETTTGVHNLYKMMSNGILKVPAINVNDSVTKSKFDNLYGCRESLIDGIKRATDVMIAGKVAVVAGYGDVGKGCAQALRGFGARVIITEIDPINALQAAMEGYEVTTMDEACKEGNIFVTTTGCVDIILGRHFEQMKDDAIVCNIGHFDVEIDVKWLNENAVEKVNIKPQVDRYWLKNGRRIILLAEGRLVNLGCAMGHPSFVMSNSFTNQVMAQIELWTHPDKYPVGVHFLPKKLDEAVAEAHLGKLNVKLTKLTEKQAQYLGMPINGPFKPDHYRY