5ael A 2.6 BS01 QAF A 1 Y99 D103 D107 R112 A169 Q172 K212 D255 K269 Y89 D93 D97 R102 A159 Q162 K202 D245 K259 K47 H98 D103 D107 R112 D175 K212 F251 D255 D256 K47 H88 D93 D97 R102 D165 K202 F241 D245 D246 2.5.1.10 0004161,0004337,0004659,0005737,0008299,0016740,0016765,0045337,0046872 -logKd/Ki=7.41, Kd=39.2nM Q86C09 26392508 1368 MPMQMFMQVYDEIQMFLLEELELKFDMDPNRVRYLRKMMDTTCLGGKYNRGLTVIDVAESLLSDGARRKRVLHDACVCGWMIEFLQAHYLVEDDIMDNSVTRRGKPCWYRHPDVTVQCAINDGLLLKSWTHMMAMHFFADRPFLQDLLCRFNRVDYTTAVGQLYDVTSMFDSNKLDPDVSQPTTTDFAEFTLSNYKRIVKYKTAYYTYLLPLVMGLIVSEALPTVDMGVTEELAMLMGEYFQVQDDVMDCFTPPERLGKVGTDIQDAKCSWLAVTFLAKASSAQVAEFKANYGSGDSEKVATVRRLYEEADLQGDYVAYEAAVAEQVKELIEKLRLCSPGFAASVETLWGKTYKRQK 5ael A 2.6 BS02 MG A 1 D103 D107 D93 D97 K47 H98 D103 D107 R112 D175 K212 F251 D255 D256 K47 H88 D93 D97 R102 D165 K202 F241 D245 D246 2.5.1.10 0004161,0004337,0004659,0005737,0008299,0016740,0016765,0045337,0046872 Q86C09 26392508 1369 MPMQMFMQVYDEIQMFLLEELELKFDMDPNRVRYLRKMMDTTCLGGKYNRGLTVIDVAESLLSDGARRKRVLHDACVCGWMIEFLQAHYLVEDDIMDNSVTRRGKPCWYRHPDVTVQCAINDGLLLKSWTHMMAMHFFADRPFLQDLLCRFNRVDYTTAVGQLYDVTSMFDSNKLDPDVSQPTTTDFAEFTLSNYKRIVKYKTAYYTYLLPLVMGLIVSEALPTVDMGVTEELAMLMGEYFQVQDDVMDCFTPPERLGKVGTDIQDAKCSWLAVTFLAKASSAQVAEFKANYGSGDSEKVATVRRLYEEADLQGDYVAYEAAVAEQVKELIEKLRLCSPGFAASVETLWGKTYKRQK 5ael A 2.6 BS03 MG A 2 D103 D107 D175 D93 D97 D165 K47 H98 D103 D107 R112 D175 K212 F251 D255 D256 K47 H88 D93 D97 R102 D165 K202 F241 D245 D246 2.5.1.10 0004161,0004337,0004659,0005737,0008299,0016740,0016765,0045337,0046872 Q86C09 26392508 1371 MPMQMFMQVYDEIQMFLLEELELKFDMDPNRVRYLRKMMDTTCLGGKYNRGLTVIDVAESLLSDGARRKRVLHDACVCGWMIEFLQAHYLVEDDIMDNSVTRRGKPCWYRHPDVTVQCAINDGLLLKSWTHMMAMHFFADRPFLQDLLCRFNRVDYTTAVGQLYDVTSMFDSNKLDPDVSQPTTTDFAEFTLSNYKRIVKYKTAYYTYLLPLVMGLIVSEALPTVDMGVTEELAMLMGEYFQVQDDVMDCFTPPERLGKVGTDIQDAKCSWLAVTFLAKASSAQVAEFKANYGSGDSEKVATVRRLYEEADLQGDYVAYEAAVAEQVKELIEKLRLCSPGFAASVETLWGKTYKRQK 5ael B 2.6 BS01 QAF B 1 Y99 D103 D107 R112 A169 Q172 K212 D255 K269 Y89 D93 D97 R102 A159 Q162 K202 D245 K259 K47 H98 D103 D107 R112 D175 K212 F251 D255 D256 K47 H88 D93 D97 R102 D165 K202 F241 D245 D246 2.5.1.10 0004161,0004337,0004659,0005737,0008299,0016740,0016765,0045337,0046872 -logKd/Ki=7.41, Kd=39.2nM Q86C09 26392508 1368 MPMQMFMQVYDEIQMFLLEELELKFDMDPNRVRYLRKMMDTTCLGGKYNRGLTVIDVAESLLSDGARRKRVLHDACVCGWMIEFLQAHYLVEDDIMDNSVTRRGKPCWYRHPDVTVQCAINDGLLLKSWTHMMAMHFFADRPFLQDLLCRFNRVDYTTAVGQLYDVTSMFDSNKLDPDVSQPTTTDFAEFTLSNYKRIVKYKTAYYTYLLPLVMGLIVSEALPTVDMGVTEELAMLMGEYFQVQDDVMDCFTPPERLGKVGTDIQDAKCSWLAVTFLAKASSAQVAEFKANYGSGDSEKVATVRRLYEEADLQGDYVAYEAAVAEQVKELIEKLRLCSPGFAASVETLWGKTYKRQK 5ael B 2.6 BS02 MG B 1 D103 D107 D93 D97 K47 H98 D103 D107 R112 D175 K212 F251 D255 D256 K47 H88 D93 D97 R102 D165 K202 F241 D245 D246 2.5.1.10 0004161,0004337,0004659,0005737,0008299,0016740,0016765,0045337,0046872 Q86C09 26392508 1369 MPMQMFMQVYDEIQMFLLEELELKFDMDPNRVRYLRKMMDTTCLGGKYNRGLTVIDVAESLLSDGARRKRVLHDACVCGWMIEFLQAHYLVEDDIMDNSVTRRGKPCWYRHPDVTVQCAINDGLLLKSWTHMMAMHFFADRPFLQDLLCRFNRVDYTTAVGQLYDVTSMFDSNKLDPDVSQPTTTDFAEFTLSNYKRIVKYKTAYYTYLLPLVMGLIVSEALPTVDMGVTEELAMLMGEYFQVQDDVMDCFTPPERLGKVGTDIQDAKCSWLAVTFLAKASSAQVAEFKANYGSGDSEKVATVRRLYEEADLQGDYVAYEAAVAEQVKELIEKLRLCSPGFAASVETLWGKTYKRQK 5ael B 2.6 BS03 MG B 2 D103 D107 D93 D97 K47 H98 D103 D107 R112 D175 K212 F251 D255 D256 K47 H88 D93 D97 R102 D165 K202 F241 D245 D246 2.5.1.10 0004161,0004337,0004659,0005737,0008299,0016740,0016765,0045337,0046872 Q86C09 26392508 1371 MPMQMFMQVYDEIQMFLLEELELKFDMDPNRVRYLRKMMDTTCLGGKYNRGLTVIDVAESLLSDGARRKRVLHDACVCGWMIEFLQAHYLVEDDIMDNSVTRRGKPCWYRHPDVTVQCAINDGLLLKSWTHMMAMHFFADRPFLQDLLCRFNRVDYTTAVGQLYDVTSMFDSNKLDPDVSQPTTTDFAEFTLSNYKRIVKYKTAYYTYLLPLVMGLIVSEALPTVDMGVTEELAMLMGEYFQVQDDVMDCFTPPERLGKVGTDIQDAKCSWLAVTFLAKASSAQVAEFKANYGSGDSEKVATVRRLYEEADLQGDYVAYEAAVAEQVKELIEKLRLCSPGFAASVETLWGKTYKRQK