4zy4 A 2.6 BS01 4T3 A 1 A297 E345 Y346 L347 A348 G350 L396 A49 E92 Y93 L94 A95 G97 L143 N389 K391 D393 N394 D407 P416 T427 N136 K138 D140 N141 D154 P163 T174 2.7.11.1 0004672,0005524,0006468 -logKd/Ki=7.66, Ki=22nM Ki=22nM Q13153 26030457 601 SDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRNIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQHQFLKIAKPLSSLTPLIAAAKEAT 4zy4 B 2.6 BS01 4T3 B 1 A297 Y346 L347 A348 G350 D393 L396 T406 D407 A49 Y97 L98 A99 G101 D144 L147 T157 D158 N389 K391 D393 N394 D407 P416 T427 N140 K142 D144 N145 D158 P167 T178 2.7.11.1 0004672,0005524,0006468 Ki=22nM Q13153 26030457 601 SDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRNIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQHQFLKIAKPLSSLTPLIAAAKEAT