4zk5 A 2.89 BS01 MG A 1 S77 H79 I82 T84 S61 H63 I66 T68 D153 K155 Q157 N158 D171 T191 D137 K139 Q141 N142 D155 T166 2.7.11.1 0004672,0005524,0006468 O95819 26288693 401 SLRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTEDEEEEIKLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNTKGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTENAEVKLVDFGVSANTFIGTPYWMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLKSKKWSKKFFSFIEGCLVKNYMQRPSTEQLLKHPFIRDQPNERQVRIQLKDHIDRTRK 4zk5 A 2.89 BS02 4P4 A 1 V31 Y36 V39 K41 A52 K54 M105 F107 C108 G109 G111 L160 V170 D171 V15 Y20 V23 K25 A36 K38 M89 F91 C92 G93 G95 L144 V154 D155 D153 K155 Q157 N158 D171 T191 D137 K139 Q141 N142 D155 T166 2.7.11.1 0004672,0005524,0006468 -logKd/Ki=8.43, IC50=3.7nM IC50=3.7nM O95819 26288693 403 SLRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTEDEEEEIKLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNTKGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTENAEVKLVDFGVSANTFIGTPYWMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLKSKKWSKKFFSFIEGCLVKNYMQRPSTEQLLKHPFIRDQPNERQVRIQLKDHIDRTRK