4zjr A 2.702 BS01 4P3 A 1 W317 C320 H323 L324 M365 F378 E379 F388 I397 I400 F401 W53 C56 H59 L60 M101 F114 E115 F124 I133 I136 F137 ? 0003677,0004879,0005634,0006355 -logKd/Ki=7.54, IC50=0.029uM EC50=93nM, IC50=11nM P51449 26048806 501 ASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLCKTHRQSILAKLPPKGKLRSLCSQHVE 4zjr B 2.702 BS01 4P3 B 1 W317 C320 H323 M365 V376 F378 E379 F388 I397 H479 W53 C56 H59 M101 V112 F114 E115 F124 I133 H215 ? 0003677,0004879,0005634,0006355 EC50=93nM, IC50=11nM P51449 26048806 501 ASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLCKTHRQSILAKLPPKGKLRSLCSQHVERLQ 4zjr C 2.702 BS01 4P3 C 1 C320 H323 E379 F388 L391 C393 L396 I397 I400 F401 H479 C57 H60 E116 F125 L128 C130 L133 I134 I137 F138 H216 ? 0003677,0004879,0005634,0006355 EC50=93nM, IC50=11nM P51449 26048806 501 SASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLCKTHRQSILAKLPPKGKLRSLCSQHVERL 4zjr D 2.702 BS01 4P3 D 1 C320 H323 M365 F377 F378 E379 F388 L396 I397 I400 F401 H479 C58 H61 M103 F115 F116 E117 F126 L134 I135 I138 F139 H217 ? 0003677,0004879,0005634,0006355 EC50=93nM, IC50=11nM P51449 26048806 501 GSASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLCKTHRQSILAKLPPKGKLRSLCSQHVE