4zcw A 1.992 BS01 4NG A 1 G38 S40 Q166 E167 D245 D318 K343 H371 R372 S373 K394 G37 S39 Q165 E166 D244 D317 K342 H370 R371 S372 K393 S40 H158 E167 E210 D245 E293 D318 K343 H371 K394 S39 H157 E166 E209 D244 E292 D317 K342 H370 K393 4.2.1.11 0000015,0000287,0001917,0004634,0005515,0005615,0005737,0005829,0005886,0006094,0006096,0016020,0016829,0043025,0043204,0046872,0061621,0070062 ic50=42.5nM -logKd/Ki=7.37, IC50=42.5nM IC50=42.5nM P09104 27723749 501 SIEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGKGVLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKAGAAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDAMRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYTEKIVIGMDVAASEFYRDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELGDEARFAGHNFRNPSVL 4zcw A 1.992 BS02 MG A 1 D245 E293 D318 D244 E292 D317 S40 H158 E167 E210 D245 E293 D318 K343 H371 K394 S39 H157 E166 E209 D244 E292 D317 K342 H370 K393 4.2.1.11 0000015,0000287,0001917,0004634,0005515,0005615,0005737,0005829,0005886,0006094,0006096,0016020,0016829,0043025,0043204,0046872,0061621,0070062 P09104 27723749 502 SIEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGKGVLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKAGAAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDAMRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYTEKIVIGMDVAASEFYRDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELGDEARFAGHNFRNPSVL 4zcw B 1.992 BS01 4NG B 1 G38 A39 S40 Q166 E167 D245 D318 K343 H371 R372 S373 K394 G37 A38 S39 Q165 E166 D244 D317 K342 H370 R371 S372 K393 S40 H158 E167 E210 D245 E293 D318 K343 H371 K394 S39 H157 E166 E209 D244 E292 D317 K342 H370 K393 4.2.1.11 0000015,0000287,0001917,0004634,0005515,0005615,0005737,0005829,0005886,0006094,0006096,0016020,0016829,0043025,0043204,0046872,0061621,0070062 ic50=42.5nM IC50=42.5nM P09104 27723749 501 SIEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGKGVLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKAGAAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDAMRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYTEKIVIGMDVAASEFYRDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELGDEARFAGHNFRNPSVL 4zcw B 1.992 BS02 MG B 1 D245 E293 D318 D244 E292 D317 S40 H158 E167 E210 D245 E293 D318 K343 H371 K394 S39 H157 E166 E209 D244 E292 D317 K342 H370 K393 4.2.1.11 0000015,0000287,0001917,0004634,0005515,0005615,0005737,0005829,0005886,0006094,0006096,0016020,0016829,0043025,0043204,0046872,0061621,0070062 P09104 27723749 503 SIEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGKGVLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKAGAAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDAMRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYTEKIVIGMDVAASEFYRDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELGDEARFAGHNFRNPSVL