4yux A 1.6 BS01 S4M A 1 Q40 Q64 H74 D98 D118 I119 V123 G150 D168 T169 T170 P175 A176 L179 Q39 Q63 H73 D97 D117 I118 V122 G149 D167 T168 T169 P174 A175 L178 2.5.1.16 0003824,0004766,0006596,0016740 Q4DA73 26327378 501 PGSELISGGWFREENDQWPGQAMSLRVEKVLYDAPTKFQHLTIFESDPKGPWGTVMALDGCIQVTDYDEFVYHEVLGHTSLCSHPKPERVLIIGGGDGGVLREVLRHGTVEHCDLVDIDGEVMEQSKQHFPQISRSLADPRATVRVGDGLAFVRQTPDNTYDVVIIDTTDPAGPASKLFGEAFYKDVLRILKPDGICCNQGESIWLDLELIEKMSRFIRETGFASVQYALMHVPTYPCGSIGTLVCSKKAGVDVTKPLRPVEDMPFAKDLKYYDSEMHKASFALPRFARHINN 4yux A 1.6 BS02 4JT A 1 I63 Q64 Y73 Q201 T236 I242 I62 Q63 Y72 Q200 T235 I241 2.5.1.16 0003824,0004766,0006596,0016740 ic50=180uM -logKd/Ki=3.74, IC50=180uM Q4DA73 26327378 502 PGSELISGGWFREENDQWPGQAMSLRVEKVLYDAPTKFQHLTIFESDPKGPWGTVMALDGCIQVTDYDEFVYHEVLGHTSLCSHPKPERVLIIGGGDGGVLREVLRHGTVEHCDLVDIDGEVMEQSKQHFPQISRSLADPRATVRVGDGLAFVRQTPDNTYDVVIIDTTDPAGPASKLFGEAFYKDVLRILKPDGICCNQGESIWLDLELIEKMSRFIRETGFASVQYALMHVPTYPCGSIGTLVCSKKAGVDVTKPLRPVEDMPFAKDLKYYDSEMHKASFALPRFARHINN 4yux B 1.6 BS01 S4M B 1 Q64 H74 D98 D118 I119 V123 G150 D168 T169 T170 P175 A176 L179 Q64 H74 D98 D118 I119 V123 G150 D168 T169 T170 P175 A176 L179 2.5.1.16 0003824,0004766,0006596,0016740 Q4DA73 26327378 501 MPGSELISGGWFREENDQWPGQAMSLRVEKVLYDAPTKFQHLTIFESDPKGPWGTVMALDGCIQVTDYDEFVYHEVLGHTSLCSHPKPERVLIIGGGDGGVLREVLRHGTVEHCDLVDIDGEVMEQSKQHFPQISRSLADPRATVRVGDGLAFVRQTPDNTYDVVIIDTTDPAGPASKLFGEAFYKDVLRILKPDGICCNQGESIWLDLELIEKMSRFIRETGFASVQYALMHVPTYPCGSIGTLVCSKKAGVDVTKPLRPVEDMPFAKDLKYYDSEMHKASFALPRFARHINN 4yux B 1.6 BS02 4JT B 1 I63 Q64 Y73 Q201 T236 Y237 I242 I63 Q64 Y73 Q201 T236 Y237 I242 2.5.1.16 0003824,0004766,0006596,0016740 ic50=180uM Q4DA73 26327378 502 MPGSELISGGWFREENDQWPGQAMSLRVEKVLYDAPTKFQHLTIFESDPKGPWGTVMALDGCIQVTDYDEFVYHEVLGHTSLCSHPKPERVLIIGGGDGGVLREVLRHGTVEHCDLVDIDGEVMEQSKQHFPQISRSLADPRATVRVGDGLAFVRQTPDNTYDVVIIDTTDPAGPASKLFGEAFYKDVLRILKPDGICCNQGESIWLDLELIEKMSRFIRETGFASVQYALMHVPTYPCGSIGTLVCSKKAGVDVTKPLRPVEDMPFAKDLKYYDSEMHKASFALPRFARHINN