4ylu A 2.1 BS01 R30 A 1 M25 H41 L49 F143 C148 H166 M168 E169 D190 K191 Q192 M25 H41 L49 F143 C148 H166 M168 E169 D190 K191 Q192 H41 G146 C148 H41 G146 C148 3.4.19.12 0008233,0019082 -logKd/Ki=4.00, IC50>100uM V9TU12 26055715 401 SGLVKMSHPSGDVEACMVQVTCGSMTLNGLWLDNTVWCPRHVMCPADQLSDPNYDALLISMTNHSFSVQKHIGAPANLRVVGHAMQGTLLKLTVDVANPSTPAYTFTTVKPGAAFSVLACYNGRPTGTFTVVMRPNYTIKGSFLCGSCGSVGYTKEGSVINFCYMHQMELANGTHTGSAFDGTMYGAFMDKQVHQVQLTDKYCSVNVVAWLYAAILNGCAWFVKPNRTSVVSFNEWALANQFTEFVGTQSVDMLAVKTGVAIEQLLYAIQQLYTGFQGKQILGSTMLEDEFTPEDVNMQIMGVV 4ylu B 2.1 BS01 R30 B 1 M25 H41 L49 F143 L144 C148 H166 M168 E169 D190 K191 M25 H41 L49 F143 L144 C148 H166 M168 E169 D190 K191 H41 G146 C148 H41 G146 C148 3.4.19.12 0008233,0019082 -logKd/Ki=4.00, IC50>100uM V9TU12 26055715 401 SGLVKMSHPSGDVEACMVQVTCGSMTLNGLWLDNTVWCPRHVMCPADQLSDPNYDALLISMTNHSFSVQKHIGAPANLRVVGHAMQGTLLKLTVDVANPSTPAYTFTTVKPGAAFSVLACYNGRPTGTFTVVMRPNYTIKGSFLCGSCGSVGYTKEGSVINFCYMHQMELANGTHTGSAFDGTMYGAFMDKQVHQVQLTDKYCSVNVVAWLYAAILNGCAWFVKPNRTSVVSFNEWALANQFTEFVGTQSVDMLAVKTGVAIEQLLYAIQQLYTGFQGKQILGSTMLEDEFTPEDVNMQIMG 4ylu C 2.1 BS01 R30 C 1 M25 H41 L49 F143 L144 C145 C148 H166 M168 E169 D190 K191 Q192 M25 H41 L49 F143 L144 C145 C148 H166 M168 E169 D190 K191 Q192 H41 G146 C148 H41 G146 C148 3.4.19.12 0008233,0019082 V9TU12 26055715 401 SGLVKMSHPSGDVEACMVQVTCGSMTLNGLWLDNTVWCPRHVMCPADQLSDPNYDALLISMTNHSFSVQKHIGAPANLRVVGHAMQGTLLKLTVDVANPSTPAYTFTTVKPGAAFSVLACYNGRPTGTFTVVMRPNYTIKGSFLCGSCGSVGYTKEGSVINFCYMHQMELANGTHTGSAFDGTMYGAFMDKQVHQVQLTDKYCSVNVVAWLYAAILNGCAWFVKPNRTSVVSFNEWALANQFTEFVGTQSVDMLAVKTGVAIEQLLYAIQQLYTGFQGKQILGSTMLEDEFTPEDVNMQIMG 4ylu D 2.1 BS01 R30 D 1 M25 H41 A46 L49 F143 L144 C145 C148 H166 M168 E169 D190 K191 Q192 M25 H41 A46 L49 F143 L144 C145 C148 H166 M168 E169 D190 K191 Q192 H41 G146 C148 H41 G146 C148 3.4.19.12 0008233,0019082 V9TU12 26055715 401 SGLVKMSHPSGDVEACMVQVTCGSMTLNGLWLDNTVWCPRHVMCPADQLSDPNYDALLISMTNHSFSVQKHIGAPANLRVVGHAMQGTLLKLTVDVANPSTPAYTFTTVKPGAAFSVLACYNGRPTGTFTVVMRPNYTIKGSFLCGSCGSVGYTKEGSVINFCYMHQMELANGTHTGSAFDGTMYGAFMDKQVHQVQLTDKYCSVNVVAWLYAAILNGCAWFVKPNRTSVVSFNEWALANQFTEFVGTQSVDMLAVKTGVAIEQLLYAIQQLYTGFQGKQILGSTMLEDEFTPEDVNMQIMGVV