4yht A 3.05 BS01 4EF A 1 I462 V470 A480 K482 T528 W530 C531 G533 N579 F582 D593 I15 V23 A33 K35 T81 W83 C84 G86 N132 F135 D146 D575 K577 N579 N580 D593 S615 D128 K130 N132 N133 D146 S155 2.7.11.1 0004672,0005524,0006468 -logKd/Ki=9.22, IC50=0.6nM IC50=0.600000nM P15056 27246618 1002 DWEIPDGQITVGQRIGSGSFGTVYKGKWHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHLHTNETKFEMTKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKGSILWMAPEVIRMQDPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPTFPQILASIETLAR 4yht B 3.05 BS01 4EF B 1 I462 V470 A480 K482 T528 W530 C531 N579 F582 D593 I15 V23 A33 K35 T81 W83 C84 N132 F135 D146 D575 K577 N579 N580 D593 S615 D128 K130 N132 N133 D146 S156 2.7.11.1 0004672,0005524,0006468 IC50=0.600000nM P15056 27246618 802 DWEIPDGQITVGQRIGSGSFGTVYKGKWHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHLHTNETKFEMTKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSGSILWMAPEVIRMQDPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPTFPQILASIETLARS