4y73 A 2.14 BS01 XPY A 1 M192 E194 V200 A211 Y262 M265 G268 A315 L318 D329 M30 E32 V38 A49 Y100 M103 G106 A153 L156 D167 D311 K313 A315 N316 D329 T351 D149 K151 A153 N154 D167 T184 2.7.11.1 0000287,0004672,0004674,0005524,0006468,0007165 ic50=0.3nM -logKd/Ki=9.52, IC50=0.3nM IC50=0.300000nM Q9NWZ3 26101574 1000 TRFHSFSFYELKNVTNNFDERPISVGGNKMGEGGFGVVYKGYVNNTTVAVKKLAAMVDITTEELKQQFDQEIKVMAKCQHENLVELLGFSSDGDDLCLVYVYMPNGSLLDRLSCLDGTPPLSWHMRCKIAQGAANGINFLHENHHIHRDIKSANILLDEAFTAKISDFGLARASTVMTSRIVGTTAYMAPEALRGEITPKSDIYSFGVVLLEIITGLPAVDEHREPQLLLDIKEEIEDEEKTIEDYIDKKMNDADSTSVEAMYSVASQCLHEKKNKRPDIKKVQQLLQEMTA 4y73 B 2.14 BS01 XPY B 1 M192 E194 V200 A211 Y262 M265 G268 A315 L318 D329 M32 E34 V40 A51 Y102 M105 G108 A155 L158 D169 D311 K313 A315 N316 D329 T351 D151 K153 A155 N156 D169 T184 2.7.11.1 0000287,0004672,0004674,0005524,0006468,0007165 ic50=0.3nM IC50=0.300000nM Q9NWZ3 26101574 1000 SDTRFHSFSFYELKNVTNNFDERPISVGGNKMGEGGFGVVYKGYVNNTTVAVKKLAAMVDITTEELKQQFDQEIKVMAKCQHENLVELLGFSSDGDDLCLVYVYMPNGSLLDRLSCLDGTPPLSWHMRCKIAQGAANGINFLHENHHIHRDIKSANILLDEAFTAKISDFGLARTVMTSRIVGTTAYMAPEALRGEITPKSDIYSFGVVLLEIITGLPAVDEHREPQLLLDIKEEIEDEEKTIEDYIDKKMNDADSTSVEAMYSVASQCLHEKKNKRPDIKKVQQLLQEMTA 4y73 C 2.14 BS01 XPY C 1 M192 E194 V200 A211 Y262 M265 G268 A315 L318 D329 M29 E31 V37 A48 Y99 M102 G105 A152 L155 D166 D311 K313 A315 N316 D329 T351 D148 K150 A152 N153 D166 T184 2.7.11.1 0000287,0004672,0004674,0005524,0006468,0007165 ic50=0.3nM IC50=0.300000nM Q9NWZ3 26101574 1000 RFHSFSFYELKNVTNNFDERPISVGGNKMGEGGFGVVYKGYVNNTTVAVKKLAAMVDITTEELKQQFDQEIKVMAKCQHENLVELLGFSSDGDDLCLVYVYMPNGSLLDRLSCLDGTPPLSWHMRCKIAQGAANGINFLHENHHIHRDIKSANILLDEAFTAKISDFGLARASETVMTSRIVGTTAYMAPEALRGEITPKSDIYSFGVVLLEIITGLPAVDEHREPQLLLDIKEEIEDEEKTIEDYIDKKMNDADSTSVEAMYSVASQCLHEKKNKRPDIKKVQQLLQEMTAS 4y73 D 2.14 BS01 XPY D 1 M192 E194 V200 A211 K213 Y262 M265 G268 A315 L318 D329 M29 E31 V37 A48 K50 Y99 M102 G105 A152 L155 D166 D311 K313 A315 N316 D329 T351 D148 K150 A152 N153 D166 T183 2.7.11.1 0000287,0004672,0004674,0005524,0006468,0007165 ic50=0.3nM IC50=0.300000nM Q9NWZ3 26101574 1000 RFHSFSFYELKNVTNNFDERPISVGGNKMGEGGFGVVYKGYVNNTTVAVKKLAAMVDITTEELKQQFDQEIKVMAKCQHENLVELLGFSSDGDDLCLVYVYMPNGSLLDRLSCLDGTPPLSWHMRCKIAQGAANGINFLHENHHIHRDIKSANILLDEAFTAKISDFGLARASTVMTSRIVGTTAYMAPEALRGEITPKSDIYSFGVVLLEIITGLPAVDEHREPQLLLDIKEEIEDEEKTIEDYIDKKMNDADSTSVEAMYSVASQCLHEKKNKRPDIKKVQQLLQEMTA