4y2s A 2.3 BS01 MG A 1 D9 D11 D185 D8 D10 D184 F267 H334 D335 W336 N359 N378 Y383 Y466 D496 H524 F266 H333 D334 W335 N358 N377 Y382 Y465 D495 H523 3.1.3.76,3.3.2.10 0000287,0003824,0004301,0005737,0005777,0005782,0005829,0006629,0009056,0009636,0010628,0015643,0016311,0016787,0016791,0033885,0042577,0042632,0042803,0046272,0046839,0046872,0052642,0070062,0090181,0097176 P34913 25862210 601 TLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITLSQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSDAR 4y2s A 2.3 BS02 49P A 1 F267 Y383 F497 V498 H524 F266 Y382 F496 V497 H523 F267 H334 D335 W336 N359 N378 Y383 Y466 D496 H524 F266 H333 D334 W335 N358 N377 Y382 Y465 D495 H523 3.1.3.76,3.3.2.10 0000287,0003824,0004301,0005737,0005777,0005782,0005829,0006629,0009056,0009636,0010628,0015643,0016311,0016787,0016791,0033885,0042577,0042632,0042803,0046272,0046839,0046872,0052642,0070062,0090181,0097176 ic50=52uM -logKd/Ki=4.28, IC50=52uM IC50=52000nM P34913 25862210 602 TLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITLSQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSDAR