4y2h A 2.37 BS01 SAH A 1 Y47 Y48 Y51 M60 R66 G90 A91 L96 E112 A113 P139 V140 E141 M166 S169 Y9 Y10 Y13 M22 R28 G52 A53 L58 E74 A75 P101 V102 E103 M128 S131 D63 E155 E164 H317 D25 E117 E126 H279 2.1.1.319 0000122,0003682,0005515,0005634,0005654,0005730,0006281,0006284,0006325,0006338,0008168,0008469,0010821,0016274,0018216,0032259,0035241,0035242,0036211,0042054,0042393,0044020,0045652,0045892,0070611,0070612,0090398,0140938,1901796,2000059 Q96LA8 26101569 401 TKRERDQLYYECYSDVSVHEEMIADRVRTDAYRLGILRNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQAREVVRFNGLEDRVHVLPGPVETVELPEQVDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLLPASAELFIAPISDQMLEWRLGFWSQVKQHYGVDMSCLEGFATRCLMGHSEIVVQGLSGEDVLARPQRFAQLELSRAGLEQELEAGVGGRFRCSCYGSAPMHGFAIWFQVTFPGGESEKPLVLSTSPFHPATHWKQALLYLNEPVQVEQDTDVSGEITLLPSRDNPRRLRVLLRYKVGDQEEKTKDFAMED 4y2h A 2.37 BS02 49K A 1 Y51 V56 E59 M60 E155 M157 Y159 E164 H317 Y13 V18 E21 M22 E117 M119 Y121 E126 H279 D63 E155 E164 H317 D25 E117 E126 H279 2.1.1.319 0000122,0003682,0005515,0005634,0005654,0005730,0006281,0006284,0006325,0006338,0008168,0008469,0010821,0016274,0018216,0032259,0035241,0035242,0036211,0042054,0042393,0044020,0045652,0045892,0070611,0070612,0090398,0140938,1901796,2000059 ic50=0.011uM IC50=11nM Q96LA8 26101569 402 TKRERDQLYYECYSDVSVHEEMIADRVRTDAYRLGILRNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQAREVVRFNGLEDRVHVLPGPVETVELPEQVDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLLPASAELFIAPISDQMLEWRLGFWSQVKQHYGVDMSCLEGFATRCLMGHSEIVVQGLSGEDVLARPQRFAQLELSRAGLEQELEAGVGGRFRCSCYGSAPMHGFAIWFQVTFPGGESEKPLVLSTSPFHPATHWKQALLYLNEPVQVEQDTDVSGEITLLPSRDNPRRLRVLLRYKVGDQEEKTKDFAMED 4y2h B 2.37 BS01 SAH B 1 Y51 M60 R66 G90 A91 I95 L96 E112 A113 P139 V140 E141 E155 M166 S169 Y28 M37 R43 G67 A68 I72 L73 E89 A90 P116 V117 E118 E132 M143 S146 D63 E155 E164 H317 D40 E132 E141 H294 2.1.1.319 0000122,0003682,0005515,0005634,0005654,0005730,0006281,0006284,0006325,0006338,0008168,0008469,0010821,0016274,0018216,0032259,0035241,0035242,0036211,0042054,0042393,0044020,0045652,0045892,0070611,0070612,0090398,0140938,1901796,2000059 Q96LA8 26101569 401 SIAAEREAALERPRRTKRERDQLYYECYSDVSVHEEMIADRVRTDAYRLGILRNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQAREVVRFNGLEDRVHVLPGPVETVELPEQVDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLLPASAELFIAPISDQMLEWRLGFWSQVKQHYGVDMSCLEGFATRCLMGHSEIVVQGLSGEDVLARPQRFAQLELSRAGLEQELEAGVGGRFRCSCYGSAPMHGFAIWFQVTFPGGESEKPLVLSTSPFHPATHWKQALLYLNEPVQVEQDTDVSGEITLLPSRDNPRRLRVLLRYKVGDQEEKTKDFAMED 4y2h B 2.37 BS02 49K B 1 Y51 V56 E59 M60 E155 M157 Y159 E164 H317 Y28 V33 E36 M37 E132 M134 Y136 E141 H294 D63 E155 E164 H317 D40 E132 E141 H294 2.1.1.319 0000122,0003682,0005515,0005634,0005654,0005730,0006281,0006284,0006325,0006338,0008168,0008469,0010821,0016274,0018216,0032259,0035241,0035242,0036211,0042054,0042393,0044020,0045652,0045892,0070611,0070612,0090398,0140938,1901796,2000059 ic50=0.011uM IC50=11nM Q96LA8 26101569 402 SIAAEREAALERPRRTKRERDQLYYECYSDVSVHEEMIADRVRTDAYRLGILRNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQAREVVRFNGLEDRVHVLPGPVETVELPEQVDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLLPASAELFIAPISDQMLEWRLGFWSQVKQHYGVDMSCLEGFATRCLMGHSEIVVQGLSGEDVLARPQRFAQLELSRAGLEQELEAGVGGRFRCSCYGSAPMHGFAIWFQVTFPGGESEKPLVLSTSPFHPATHWKQALLYLNEPVQVEQDTDVSGEITLLPSRDNPRRLRVLLRYKVGDQEEKTKDFAMED