4xi3 A 2.491 BS01 29S A 1 T347 D351 L391 F404 I424 H524 L525 P535 T35 D39 L79 F92 I112 H209 L210 P220 ? IC50=50nM P03372 30489256 601 LALSLTADQMVSALLDAEPPILYSEYDPSMMGLLTNLADRELVHMINWAKRVPGFVDLTSHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPSYDLLLEMLD 4xi3 B 2.491 BS01 29S B 1 T347 A350 D351 L354 W383 F404 I424 H524 L525 V533 P535 T41 A44 D45 L48 W77 F98 I118 H214 L215 V221 P223 ? IC50=50nM P03372 30489256 601 ALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTSHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKNVVPSYDLLLEMLD 4xi3 C 2.491 BS01 29S C 1 L346 T347 A350 D351 E353 L354 W383 M388 R394 F404 I424 H524 V533 P535 L41 T42 A45 D46 E48 L49 W78 M83 R89 F99 I119 H215 V224 P226 ? IC50=50nM P03372 30489256 601 LALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTSHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPSYDLLLEMLD 4xi3 D 2.491 BS01 29S D 1 A350 D351 E353 L354 W383 L387 F404 I424 H524 L525 N532 A38 D39 E41 L42 W71 L75 F92 I112 H200 L201 N208 ? IC50=50nM P03372 30489256 601 LALSLTADQMVSALLDAEPPILYSEYDPSMMGLLTNLADRELVHMINWAKRVPGFVDLTSHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPSYDLLLEM