4xhe A 1.9 BS01 40P A 1 Y93 W147 V148 Y188 Y195 Y101 W155 V156 Y196 Y203 ? 0004888,0005216,0005230,0006811,0016020,0034220 -logKd/Ki=10.30, Kd<0.05nM Q8WSF8 26004441 301 YKDDDDKLHSQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR 4xhe A 1.9 BS02 40P B 1 T36 Y55 I118 T44 Y63 I126 ? 0004888,0005216,0005230,0006811,0016020,0034220 -logKd/Ki=10.30, Kd<0.05nM Q8WSF8 26004441 301 YKDDDDKLHSQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR 4xhe B 1.9 BS01 40P B 1 Y93 W147 V148 Y188 Y195 Y102 W156 V157 Y197 Y204 ? 0004888,0005216,0005230,0006811,0016020,0034220 Q8WSF8 26004441 301 DYKDDDDKLHSQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR 4xhe B 1.9 BS02 CA B 1 K-6 D-3 D-2 N70 K3 D6 D7 N79 ? 0004888,0005216,0005230,0006811,0016020,0034220 Q8WSF8 26004441 302 DYKDDDDKLHSQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR 4xhe B 1.9 BS03 40P C 1 Y55 I118 S167 Y64 I127 S176 ? 0004888,0005216,0005230,0006811,0016020,0034220 Q8WSF8 26004441 301 DYKDDDDKLHSQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR 4xhe C 1.9 BS01 40P C 1 Y93 W147 V148 Y188 Y195 Y96 W150 V151 Y191 Y198 ? 0004888,0005216,0005230,0006811,0016020,0034220 Q8WSF8 26004441 301 DKLHSQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR 4xhe C 1.9 BS02 40P D 1 Y55 I118 S167 Y58 I121 S170 ? 0004888,0005216,0005230,0006811,0016020,0034220 Q8WSF8 26004441 301 DKLHSQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR 4xhe D 1.9 BS01 40P D 1 Y93 W147 V148 Y195 Y96 W150 V151 Y198 ? 0004888,0005216,0005230,0006811,0016020,0034220 Q8WSF8 26004441 301 DKLHSQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR 4xhe D 1.9 BS02 40P E 1 Y55 I118 S167 Y58 I121 S170 ? 0004888,0005216,0005230,0006811,0016020,0034220 Q8WSF8 26004441 301 DKLHSQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR 4xhe E 1.9 BS01 40P A 1 Y55 I118 S167 Y58 I121 S170 ? 0004888,0005216,0005230,0006811,0016020,0034220 -logKd/Ki=10.30, Kd<0.05nM Q8WSF8 26004441 301 DKLHSQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRER 4xhe E 1.9 BS02 40P E 1 Y93 W147 V148 Y195 Y96 W150 V151 Y198 ? 0004888,0005216,0005230,0006811,0016020,0034220 -logKd/Ki=10.30, Kd<0.05nM Q8WSF8 26004441 301 DKLHSQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRER 4xhe F 1.9 BS01 40P F 1 Y93 W147 V148 Y188 Y195 Y98 W152 V153 Y193 Y200 ? 0004888,0005216,0005230,0006811,0016020,0034220 Q8WSF8 26004441 301 DDDKLHSQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR 4xhe F 1.9 BS02 40P G 1 Y55 I118 Y60 I123 ? 0004888,0005216,0005230,0006811,0016020,0034220 Q8WSF8 26004441 301 DDDKLHSQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR 4xhe G 1.9 BS01 40P G 1 Y93 W147 V148 Y188 Y195 Y96 W150 V151 Y191 Y198 ? 0004888,0005216,0005230,0006811,0016020,0034220 Q8WSF8 26004441 301 DKLHSQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRER 4xhe G 1.9 BS02 40P H 1 Y55 I118 S167 Y58 I121 S170 ? 0004888,0005216,0005230,0006811,0016020,0034220 Q8WSF8 26004441 301 DKLHSQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRER 4xhe H 1.9 BS01 40P H 1 Y93 W147 V148 Y188 Y195 Y97 W151 V152 Y192 Y199 ? 0004888,0005216,0005230,0006811,0016020,0034220 Q8WSF8 26004441 301 DDKLHSQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR 4xhe H 1.9 BS02 40P I 1 Y55 I118 S167 Y59 I122 S171 ? 0004888,0005216,0005230,0006811,0016020,0034220 Q8WSF8 26004441 301 DDKLHSQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR 4xhe I 1.9 BS01 40P I 1 Y93 W147 V148 Y188 Y195 Y90 W144 V145 Y185 Y192 ? 0004888,0005216,0005230,0006811,0016020,0034220 Q8WSF8 26004441 301 LHSQANLMRLKSDLFNYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRER 4xhe I 1.9 BS02 40P J 1 Y55 I118 S167 Y52 I115 S164 ? 0004888,0005216,0005230,0006811,0016020,0034220 Q8WSF8 26004441 301 LHSQANLMRLKSDLFNYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRER 4xhe J 1.9 BS01 40P F 1 Y55 I118 Y58 I121 ? 0004888,0005216,0005230,0006811,0016020,0034220 Q8WSF8 26004441 301 DKLHSQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR 4xhe J 1.9 BS02 40P J 1 Y93 W147 V148 Y195 Y96 W150 V151 Y198 ? 0004888,0005216,0005230,0006811,0016020,0034220 Q8WSF8 26004441 301 DKLHSQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR